VariantGrid is a database and web application for storing, analysing and classifying variants.
Public servers:
- VariantGrid.com - research focused instance, free user access
Collaborative data sharing sites:
- Shariant Australia - Australian Genomics variant interpretation sharing server
- RUNX1Db - Rare blood disease data sharing
Private servers:
- Clinical/diagnostic use by SA Pathology, the South Australian public pathology service.
- Research exomes by labs at the Centre for Cancer Biology
Upload VCFs to:
- Automatically annotate with Ensembl VEP
- See samples from all VCFs that share a variant
- Analyse and filter samples, trios or cohorts via real time drag & drop interactive analyses
- Classify variants using a customisable ACMG form
- GRCh37 (hg19), GRCh38, Ensembl and RefSeq in the same database (some automatic conversion)
- Manage and curate data, including patient phenotypes
VariantGrid code is free to use for research and evaluation, while production commercial use requires a licence, before code becomes fully free/open source in 4 years.
Please contact us to discuss support/collaboration.
- User guide at read the docs
- Technical Wiki wiki for installation/maintenance.
- Contact us and we can setup and manage a cloud instance for you
- Install from source/scratch
- Clone a VM (AWS, VirtualBox, NECTAR, NCBI instances)
VariantGrid is written in Python3, using Django and PostgreSQL.