refactoring and optimizations in annotations #4211

Job	Run time
MacOS (DNA, Debug, x64)	7m 43s
MacOS (DNA, Debug, arm64)	8m 2s
MacOS (DNA, Release, x64)	7m 43s
MacOS (DNA, Release, arm64)	35m 39s
Linux (DNA, Debug, g++-8)	9m 42s
Linux (DNA, Debug, g++-9)	9m 42s
Linux (DNA, Debug, g++-10)	9m 43s
Linux (DNA, Debug, g++-11)	9m 42s
Linux (DNA, Release, g++-8)	9m 42s
Linux (DNA, Release, g++-9)	9m 41s
Linux (DNA, Release, g++-10)	9m 39s
Linux (DNA, Release, g++-11)	9m 42s
Linux (DNA, Release, g++-11, static, noAVX)	9m 43s
Linux (DNA, Release, g++-11, static)	9m 42s
Linux (Protein, Debug, g++-8)	9m 42s
Linux (Protein, Debug, g++-10)	9m 42s
Linux (Protein, Debug, g++-11)	9m 44s
Linux (Protein, Release, g++-8)	9m 27s
Linux (Protein, Release, g++-10)	9m 43s
Linux (Protein, Release, g++-11)	9m 40s
Linux (Protein, Release, g++-11, static, noAVX)	9m 39s
Linux (Protein, Release, g++-11, static)	9m 40s
Test metagraph workflows	0s
Build-and-Push-Docker	0s
Create Release	0s
	3h 53m 22s

Provide feedback