This repository contains Mplus files to fit longitudinal modified latent change mediation models and Bayesian mediation models.
tcbt = binary intervention arm variable
ipqn0s ipqn1s ipqn2s ipqn3s = baseline and three post-randomisation measures of an example mediator
ibs0s ibs1s ibs2s ibs3s = baseline and three post-randomisation measures of an example outcome
The example mediator and outcome measures are from the ACTIB trial of telephone-delivered and web-delivered cognitive behavioural therapy for refractory irritable bowel syndrome.
Main trial publication: Everitt HA, Landau S, O’Reilly G on behalf of ACTIB trial group, et al. Assessing telephone-delivered cognitive–behavioural therapy (CBT) and web-delivered CBT versus treatment as usual in irritable bowel syndrome (ACTIB): a multicentre randomised trialGut 2019;68:1613-1623, doi: 10.1136/gutjnl-2018-317805
Related pilot trial of early iteration of telephone-delivered cognitive behavioural therapy: Moss-Morris R, McAlpine L, Didsbury LP, Spence MJ. A randomized controlled trial of a cognitive behavioural therapy-based self-management intervention for irritable bowel syndrome in primary care. Psychol Med. 2010 Jan;40(1):85-94. doi: 10.1017/S0033291709990195