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1.0.3
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@susannasiebert susannasiebert released this 18 Jun 20:44
v1.0.3
e2877c2

This is a hotfix release. It fixes the following issues:

  • Stop-gain mutation were previously not handled correctly. If a mutation had a * (stop gain) in the VEP Amino_acids field, pVACseq would throw an error. We now ensure that those cases are handled. pVACseq will also skip stop-gain mutations if the resulting mutant peptide sequence is not novel.
  • pVACseq would previously throw an error if multiple mutations resulted in the same consequence. This is now handled by assigning a unique identifier to each mutation.
  • We added a better warning messages if the chosen prediction algorithms and alleles MHC classes are mutually exclusive, e.g., if only class I prediction algorithms were chosen with only class II alleles. Previously, pVACseq would simply finish without producing any output or errors.
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