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def: "Catalysis of the reaction: a ribonucleoside 5'-triphosphate + 2 H2O = a ribonucleoside 5'-phosphate + 2 phosphate. This reaction consists of two distinct successive phosphate-releasing steps, with NDPs as intermediates. Apyrases are active against both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs)." [EC:3.6.1.5]
obsolete apyrase activitydefinition "Catalysis of the reaction: a ribonucleoside 5'-triphosphate + 2 H2O = a ribonucleoside 5'-phosphate + 2 phosphate. This reaction consists of two distinct successive phosphate-releasing steps, with NDPs as intermediates. Apyrases are active against both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs)."
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Here's a diff of how these changes impact the classified ontology:
Ontology comparison
Left
http://purl.obolibrary.org/obo/go.owlhttp://purl.obolibrary.org/obo/go/releases/2023-10-17/go.owlfile:/__w/go-ontology/go-ontology/src/ontology/../../reasoned-master.owl/reasoned.owlRight
http://purl.obolibrary.org/obo/go.owlhttp://purl.obolibrary.org/obo/go/releases/2023-10-17/go.owlfile:/__w/go-ontology/go-ontology/src/ontology/../../reasoned-pr.owl/reasoned.owlOntology imports
Ontology annotations
obsolete apyrase activity
http://purl.obolibrary.org/obo/GO_0004050Removed
obsolete apyrase activity deprecated true
obsolete apyrase activity comment "This term was made obsolete because it represents a gene product which can catalyze two reactions."
obsolete apyrase activity label "obsolete apyrase activity"
obsolete apyrase activity consider "GO:0017110"
obsolete apyrase activity definition "OBSOLETE. Catalysis of the reaction: ATP + 2 H2O = AMP + 2 phosphate."
database_cross_reference "EC:3.6.1.5"
database_cross_reference "MetaCyc:APYRASE-RXN"
obsolete apyrase activity consider "GO:0017111"
obsolete apyrase activity has_exact_synonym "apyrase activity"
Added
obsolete apyrase activity database_cross_reference "MetaCyc:APYRASE-RXN"
obsolete apyrase activity label "apyrase activity"
obsolete apyrase activity database_cross_reference "RHEA:36795"
obsolete apyrase activity database_cross_reference "EC:3.6.1.5"
obsolete apyrase activity definition "Catalysis of the reaction: a ribonucleoside 5'-triphosphate + 2 H2O = a ribonucleoside 5'-phosphate + 2 phosphate. This reaction consists of two distinct successive phosphate-releasing steps, with NDPs as intermediates. Apyrases are active against both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs)."
obsolete apyrase activity SubClassOf pyrophosphatase activity