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Update README.md
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changwn authored Aug 27, 2021
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Expand Up @@ -90,32 +90,23 @@ optional arguments:
--input_dir <input_directory>
The data directory for single cell input data.
--res_dir <data_directory>
The data directory for result [output]. The output of
scFEA includes two matrices, predicted metabolic flux
and metabolites stress at single cell resolution.
The data directory for result [output]. The output of scFEA includes two matrices, predicted metabolic flux and metabolites
stress at single cell resolution.
--test_file TEST_FILE
The test SC file [input]. The input of scFEA is a
single cell profile matrix, where row is gene and
column is cell. Example datasets are provided in
/data/ folder. The input can be raw counts or
normalised counts. The logarithm would be performed if
value larger than 30.
The test SC file [input]. The input of scFEA is a single cell profile matrix, where row is gene and column is cell. Example
datasets are provided in /data/ folder. The input can be raw counts or normalised counts. The logarithm would be performed
if value larger than 30.
--moduleGene_file MODULEGENE_FILE
The table contains genes for each module. We provide
human and mouse two models in scFEA. For human model,
please use module_gene_m168.csv which is
default. All candidate moduleGene
files are provided in /data/ folder.
The table contains genes for each module. We provide human and mouse two models in scFEA. For human model, please use
module_gene_m168.csv which is default. All candidate moduleGene files are provided in /data/ folder.
--stoichiometry_matrix STOICHIOMETRY_MATRIX
The table describes relationship between compounds and
modules. Each row is an intermediate metabolite and
each column is metabolic module. For human model,
please use cmMat_c70_m168.csv which is default. All
candidate stoichiometry matrices are provided in
/data/ folder.
The table describes relationship between compounds and modules. Each row is an intermediate metabolite and each column is
metabolic module. For human model, please use cmMat_171.csv which is default. All candidate stoichiometry matrices are
provided in /data/ folder.
--cName_file CNAME_FILE
The name of compounds. The table contains two rows. First row is compounds name and second row is corresponding id.
--sc_imputation {True,False}
Whether perform imputation for SC dataset (recommend
set to <True> for 10x data).
Whether perform imputation for SC dataset (recommend set to <True> for 10x data).
```
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