Merge pull request #35 from moonso/fix_obis

Fix #33 Fix #34 - GLS, RFC1 hg19 obi1
Clinical-Genomics · May 27, 2021 · 5b437be · 5b437be
2 parents f65af7a + fbd48e3
commit 5b437be
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diff --git a/CHANGELOG.md b/CHANGELOG.md
@@ -4,6 +4,7 @@ This project adheres to [Semantic Versioning](http://semver.org/).
 
 ## [x.x.x]
 Update BEAN1 documentation reference
+Update GLS and RFC1 hg19 coordinates (zero based off by one)
 
 ## [0.7.1]
 Update rank score model

diff --git a/stranger/resources/variant_catalog_grch37.json b/stranger/resources/variant_catalog_grch37.json
@@ -974,7 +974,7 @@
         "SweGenMean": 12.66,
         "SweGenStd": 4.000,
         "LocusStructure": "(GCA)*",
-        "ReferenceRegion": "2:191745599-191745646",
+        "ReferenceRegion": "2:191745598-191745646",
         "Disease": "GDPAG",
         "NormalMax": 20,
         "PathologicMin": 90
@@ -991,7 +991,7 @@
         "SweGenMean": 26.77,
         "SweGenStd": 18.68,
         "LocusStructure": "(AARRG)*",
-        "ReferenceRegion": "4:39350045-39350099",
+        "ReferenceRegion": "4:39350044-39350099",
         "Disease": "CANVAS",
         "NormalMax": 11,
         "PathologicMin": 12

diff --git a/stranger/resources/variant_catalog_hg19.json b/stranger/resources/variant_catalog_hg19.json
@@ -974,7 +974,7 @@
         "SweGenMean": 12.66,
         "SweGenStd": 4.000,
         "LocusStructure": "(GCA)*",
-        "ReferenceRegion": "chr2:191745599-191745646",
+        "ReferenceRegion": "chr2:191745598-191745646",
         "Disease": "GDPAG",
         "NormalMax": 20,
         "PathologicMin": 90
@@ -991,7 +991,7 @@
         "SweGenMean": 26.77,
         "SweGenStd": 18.68,
         "LocusStructure": "(AARRG)*",
-        "ReferenceRegion": "chr4:39350045-39350099",
+        "ReferenceRegion": "chr4:39350044-39350099",
         "Disease": "CANVAS",
         "NormalMax": 11,
         "PathologicMin": 12