diff --git a/drivers/wifi/nrfwifi/CMakeLists.txt b/drivers/wifi/nrfwifi/CMakeLists.txt
index 2e04398c892a..439263ec6151 100644
--- a/drivers/wifi/nrfwifi/CMakeLists.txt
+++ b/drivers/wifi/nrfwifi/CMakeLists.txt
@@ -319,7 +319,6 @@ zephyr_compile_definitions(
   -DNRF70_RX_MAX_DATA_SIZE=${CONFIG_NRF70_RX_MAX_DATA_SIZE}
   -DNRF70_MAX_TX_PENDING_QLEN=${CONFIG_NRF70_MAX_TX_PENDING_QLEN}
   -DNRF70_RPU_PS_IDLE_TIMEOUT_MS=${CONFIG_NRF70_RPU_PS_IDLE_TIMEOUT_MS}
-  -DNRF70_REG_DOMAIN=${CONFIG_NRF70_REG_DOMAIN}
   -DNRF70_BAND_2G_LOWER_EDGE_BACKOFF_DSSS=${CONFIG_NRF70_BAND_2G_LOWER_EDGE_BACKOFF_DSSS}
   -DNRF70_BAND_2G_LOWER_EDGE_BACKOFF_HT=${CONFIG_NRF70_BAND_2G_LOWER_EDGE_BACKOFF_HT}
   -DNRF70_BAND_2G_LOWER_EDGE_BACKOFF_HE=${CONFIG_NRF70_BAND_2G_LOWER_EDGE_BACKOFF_HE}