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polyTG enhancements #10

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rjsicko opened this issue Jun 20, 2019 · 3 comments
Open

polyTG enhancements #10

rjsicko opened this issue Jun 20, 2019 · 3 comments
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enhancement New feature or request

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@rjsicko
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rjsicko commented Jun 20, 2019

if we check polyTG job hook on a targeted mutation run, the script should check for this and simply output "polyTG not run, targeted mutation run"

"is_only_report_targeted_mutations": true,

@rjsicko rjsicko added the enhancement New feature or request label Jun 20, 2019
@rjsicko rjsicko changed the title check for polyTG on targeted run polyTG enhancements Jun 20, 2019
@rjsicko
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rjsicko commented Jun 20, 2019

also, should probably error check better in script.

failed samples, ntc etc. might be killing the script with divide by zeros etc.

@rjsicko
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rjsicko commented Oct 27, 2021

if we check polyTG job hook on a targeted mutation run, the script should check for this and simply output "polyTG not run, targeted mutation run"

"is_only_report_targeted_mutations": true,

could we get the polyT script to run on 2nd tier and then only output the calls if there is a variant called? only trouble is the VHIRT...

@rjsicko
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rjsicko commented Oct 27, 2021

another enhancement - 'action' column.
pseudocode
if(call in "haplotypes_of_interest_list"){ action="validate and report"}elif(call in "haplotypes_benign"){action="no action necessary"}else{action="unknown haplotype, validate, interpret and report if interpretation is VOUS, LP, P"}

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