ETA distribution transformations

[EmanIbrahim137]

Hello,

I am wondering how I can apply transformations of ETA distribution as box-cox in nlmixr.

Also, is there a way to use Mixture models?

thanks,
Eman

[mattfidler]

I would suggest using the same method DOI: 10.1007/s11095-009-9931-1

There is no way to use mixture models at this time.

[mattfidler]

Note for cox box this would be:

etaBox = (exp(eta.est)*thetaBox - 1)/thetaBox