From 4ac978eccf48a1566db570027a51e60350ff41b6 Mon Sep 17 00:00:00 2001 From: Pascale Gaudet Date: Fri, 24 Nov 2023 16:15:53 +0100 Subject: [PATCH 1/2] created new term for #24712 --- src/ontology/go-edit.obo | 15 +++++++++++++++ 1 file changed, 15 insertions(+) diff --git a/src/ontology/go-edit.obo b/src/ontology/go-edit.obo index fd65d1ef2d..4c90b58054 100644 --- a/src/ontology/go-edit.obo +++ b/src/ontology/go-edit.obo @@ -456507,6 +456507,21 @@ property_value: term_tracker_item "https://github.com/geneontology/go-ontology/i created_by: pg creation_date: 2023-11-23T12:37:09Z +[Term] +id: GO:0141119 +name: genome methylation maintenance following DNA replication +namespace: biological_process +def: "The process that maintains methylated cytosine in newly synthesized DNA following DNA replication. After the establishment of novel DNA methylation marks, the newly created patterns must be faithfully transmitted by maintenance DNA methyltransferases during cell division." [PMID:20142834, PMID:26077819, PMID:34968368] {comment="PMID:11005794"} +comment: CG methylation is maintained by two evolutionarily conserved core partners: (1) a maintenance DNA methyltransferase called DNMT1 in mammals and MET1 (DNA METHYLTRANSFERASE 1) in plants and (2) a cofactor named UHRF1 in mammals and VIM (VARIANT IN METHYLATION) in plants. In mammals, the maintenance of non-CG methylation typically involves DNMT3 enzymes. In plants, non-CG methylation is further divided in two classes of sequence, CHG and CHH, and requires distinct enzymatic machineries. +synonym: "DNA methylation" BROAD [] +synonym: "DNA methylation maintenance" BROAD [] +synonym: "DNA methylation maintenance following cell division" EXACT [] +synonym: "DNA methylation maintenance following DNA replication" EXACT [] +is_a: GO:0006325 ! chromatin organization +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24712" xsd:anyURI +created_by: pg +creation_date: 2023-11-24T15:03:16Z + [Term] id: GO:0150001 name: primary dendrite From 79c0d6ddcf4c1235ed555d221d1af15b3ea6da4a Mon Sep 17 00:00:00 2001 From: Pascale Gaudet Date: Fri, 24 Nov 2023 17:28:01 +0100 Subject: [PATCH 2/2] created new term for #24712 --- src/ontology/go-edit.obo | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/src/ontology/go-edit.obo b/src/ontology/go-edit.obo index 4c90b58054..30f6a020b8 100644 --- a/src/ontology/go-edit.obo +++ b/src/ontology/go-edit.obo @@ -456511,7 +456511,7 @@ creation_date: 2023-11-23T12:37:09Z id: GO:0141119 name: genome methylation maintenance following DNA replication namespace: biological_process -def: "The process that maintains methylated cytosine in newly synthesized DNA following DNA replication. After the establishment of novel DNA methylation marks, the newly created patterns must be faithfully transmitted by maintenance DNA methyltransferases during cell division." [PMID:20142834, PMID:26077819, PMID:34968368] {comment="PMID:11005794"} +def: "The process that maintains methylated cytosine in newly synthesized DNA following DNA replication. After the establishment of novel DNA methylation marks, the newly created patterns must be faithfully transmitted by maintenance DNA methyltransferases during cell division." [PMID:11005794, PMID:20142834, PMID:26077819, PMID:34968368] comment: CG methylation is maintained by two evolutionarily conserved core partners: (1) a maintenance DNA methyltransferase called DNMT1 in mammals and MET1 (DNA METHYLTRANSFERASE 1) in plants and (2) a cofactor named UHRF1 in mammals and VIM (VARIANT IN METHYLATION) in plants. In mammals, the maintenance of non-CG methylation typically involves DNMT3 enzymes. In plants, non-CG methylation is further divided in two classes of sequence, CHG and CHH, and requires distinct enzymatic machineries. synonym: "DNA methylation" BROAD [] synonym: "DNA methylation maintenance" BROAD []