diff --git a/src/ontology/imports/go-catalytic-activities-participants.obo b/src/ontology/imports/go-catalytic-activities-participants.obo
index b38d2a9b7e..0f00359769 100644
--- a/src/ontology/imports/go-catalytic-activities-participants.obo
+++ b/src/ontology/imports/go-catalytic-activities-participants.obo
@@ -30024,12 +30024,6 @@ relationship: RO:0000057 CHEBI:63690
 relationship: RO:0000057 CHEBI:63692
 relationship: RO:0000057 CHEBI:63693
 
-[Term]
-id: GO:0102299
-relationship: RO:0000057 CHEBI:15379
-relationship: RO:0000057 CHEBI:30245
-relationship: RO:0000057 CHEBI:63323
-
 [Term]
 id: GO:0102302
 relationship: RO:0000057 CHEBI:15378
@@ -33230,14 +33224,6 @@ relationship: RO:0000057 CHEBI:57945
 relationship: RO:0000057 CHEBI:77900
 relationship: RO:0000057 CHEBI:77933
 
-[Term]
-id: GO:0140397
-relationship: RO:0000057 CHEBI:15377
-relationship: RO:0000057 CHEBI:15378
-relationship: RO:0000057 CHEBI:30089
-relationship: RO:0000057 CHEBI:77950
-relationship: RO:0000057 CHEBI:77975
-
 [Term]
 id: GO:0140398
 relationship: RO:0000057 CHEBI:15377
@@ -33248,18 +33234,6 @@ relationship: RO:0000057 CHEBI:58349
 relationship: RO:0000057 CHEBI:77951
 relationship: RO:0000057 CHEBI:77976
 
-[Term]
-id: GO:0140399
-relationship: RO:0000057 CHEBI:15377
-relationship: RO:0000057 CHEBI:15378
-relationship: RO:0000057 CHEBI:15379
-relationship: RO:0000057 CHEBI:16526
-relationship: RO:0000057 CHEBI:17790
-relationship: RO:0000057 CHEBI:18171
-relationship: RO:0000057 CHEBI:2504
-relationship: RO:0000057 CHEBI:57618
-relationship: RO:0000057 CHEBI:58210
-
 [Term]
 id: GO:0140439
 relationship: RO:0000057 CHEBI:143200
diff --git a/src/ontology/imports/go-catalytic-activities-participants.owl b/src/ontology/imports/go-catalytic-activities-participants.owl
index 1a1eb02d27..65375e88d0 100644
--- a/src/ontology/imports/go-catalytic-activities-participants.owl
+++ b/src/ontology/imports/go-catalytic-activities-participants.owl
@@ -9248,12 +9248,6 @@
     
 
 
-    <!-- http://purl.obolibrary.org/obo/CHEBI_2504 -->
-
-    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_2504"/>
-    
-
-
     <!-- http://purl.obolibrary.org/obo/CHEBI_25224 -->
 
     <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_25224"/>
@@ -21386,12 +21380,6 @@
     
 
 
-    <!-- http://purl.obolibrary.org/obo/CHEBI_63323 -->
-
-    <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_63323"/>
-    
-
-
     <!-- http://purl.obolibrary.org/obo/CHEBI_63325 -->
 
     <owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_63325"/>
@@ -163492,31 +163480,6 @@
     
 
 
-    <!-- http://purl.obolibrary.org/obo/GO_0102299 -->
-
-    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0102299">
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15379"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_30245"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_63323"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-    </owl:Class>
-    
-
-
     <!-- http://purl.obolibrary.org/obo/GO_0102302 -->
 
     <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0102302">
@@ -178394,43 +178357,6 @@
     
 
 
-    <!-- http://purl.obolibrary.org/obo/GO_0140397 -->
-
-    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0140397">
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15377"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15378"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_30089"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_77950"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_77975"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-    </owl:Class>
-    
-
-
     <!-- http://purl.obolibrary.org/obo/GO_0140398 -->
 
     <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0140398">
@@ -178480,67 +178406,6 @@
     
 
 
-    <!-- http://purl.obolibrary.org/obo/GO_0140399 -->
-
-    <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0140399">
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15377"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15378"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15379"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_16526"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17790"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_18171"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_2504"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_57618"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-        <rdfs:subClassOf>
-            <owl:Restriction>
-                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
-                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_58210"/>
-            </owl:Restriction>
-        </rdfs:subClassOf>
-    </owl:Class>
-    
-
-
     <!-- http://purl.obolibrary.org/obo/GO_0140439 -->
 
     <owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0140439">