diff --git a/src/ontology/go-edit.obo b/src/ontology/go-edit.obo index 1da795e15c..f58a361a47 100644 --- a/src/ontology/go-edit.obo +++ b/src/ontology/go-edit.obo @@ -50982,8 +50982,10 @@ id: GO:0005254 name: chloride channel activity namespace: molecular_function def: "Enables the energy-independent facilitated diffusion of a chloride ion through a transmembrane aqueous pore or channel." [GOC:mtg_transport, GOC:pr, ISBN:0815340729] +xref: RHEA:29823 {source="skos:broadMatch"} intersection_of: GO:0015267 ! channel activity intersection_of: has_primary_input CHEBI:17996 ! chloride +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0005260 @@ -51022,29 +51024,35 @@ id: GO:0005262 name: calcium channel activity namespace: molecular_function def: "Enables the energy-independent facilitated diffusion of a calcium ion through a transmembrane aqueous pore or channel." [GOC:mtg_transport, GOC:pr, ISBN:0815340729] +xref: RHEA:29671 {source="skos:broadMatch"} intersection_of: GO:0015267 ! channel activity intersection_of: has_primary_input CHEBI:29108 ! calcium(2+) relationship: part_of GO:0070588 ! calcium ion transmembrane transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0005267 name: potassium channel activity namespace: molecular_function def: "Enables the energy-independent facilitated diffusion of a potassium ion through a transmembrane aqueous pore or channel." [GOC:BHF, GOC:mtg_transport, GOC:pr, ISBN:0815340729] +xref: RHEA:29463 {source="skos:broadMatch"} is_a: GO:0005261 ! monoatomic cation channel activity is_a: GO:0015079 ! potassium ion transmembrane transporter activity intersection_of: GO:0015267 ! channel activity intersection_of: has_primary_input CHEBI:29103 ! potassium(1+) relationship: part_of GO:0071805 ! potassium ion transmembrane transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0005272 name: sodium channel activity namespace: molecular_function def: "Enables the energy-independent facilitated diffusion of a sodium ion through a transmembrane aqueous pore or channel." [GOC:BHF, GOC:mtg_transport, GOC:pr, ISBN:0815340729] +xref: RHEA:34963 {source="skos:broadMatch"} intersection_of: GO:0015267 ! channel activity intersection_of: has_primary_input CHEBI:29101 ! sodium(1+) relationship: part_of GO:0035725 ! sodium ion transmembrane transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0005274 @@ -51360,11 +51368,11 @@ synonym: "glutamate transmembrane transporter activity" BROAD [] synonym: "glutamate/aspartate porter activity" NARROW [] synonym: "glutamate/aspartate:sodium symporter activity" NARROW [] synonym: "L-glutamate transporter activity" BROAD [] -xref: RHEA:66336 {source="skos:broadMatch"} is_a: GO:0015172 ! acidic amino acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:29985 ! L-glutamate(1-) relationship: part_of GO:0015813 ! L-glutamate transmembrane transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0005314 @@ -51373,9 +51381,9 @@ namespace: molecular_function def: "Enables the transfer of glutamate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [TC:2.A.3.10.5] synonym: "high-affinity glutamate transmembrane transporter activity" BROAD [] synonym: "high-affinity glutamate transporter activity" BROAD [] -xref: RHEA:66336 {source="skos:broadMatch"} is_a: GO:0005313 ! L-glutamate transmembrane transporter activity is_a: GO:0015370 ! solute:sodium symporter activity +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0005315 @@ -51385,11 +51393,11 @@ alt_id: GO:0005317 alt_id: GO:1901677 def: "Enables the transfer of phosphate ions from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters." [GOC:mtg_transport] synonym: "inorganic phosphate transmembrane transporter activity" EXACT [] -xref: RHEA:32823 is_a: GO:0015291 ! secondary active transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:43474 ! hydrogenphosphate property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27121" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0005316 @@ -51743,13 +51751,13 @@ relationship: part_of GO:0015755 ! fructose transmembrane transport id: GO:0005354 name: galactose transmembrane transporter activity namespace: molecular_function -def: "Enables the transfer of galactose from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose." [GOC:ai, GOC:mtg_transport, ISBN:0815340729, RHEA:34915] +def: "Enables the transfer of galactose from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "galactose/glucose (methylgalactoside) porter activity" RELATED [] -xref: RHEA:34915 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:28260 ! galactose relationship: part_of GO:0015757 ! galactose transmembrane transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24076" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0005355 @@ -51842,10 +51850,10 @@ namespace: molecular_function alt_id: GO:0015581 def: "Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] synonym: "maltose porter activity" EXACT [] -xref: RHEA:33171 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:17306 ! maltose relationship: part_of GO:0015768 ! maltose transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0005364 @@ -51955,10 +51963,10 @@ def: "Enables the transfer of copper (Cu) ions from one side of a membrane to th synonym: "copper uptake transmembrane transporter activity" RELATED [] synonym: "intracellular copper ion transporter" NARROW [] synonym: "plasma membrane copper transporter" NARROW [] -xref: RHEA:28703 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:23378 ! copper cation relationship: part_of GO:0035434 ! copper ion transmembrane transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0005376 @@ -52010,11 +52018,11 @@ name: manganese ion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of manganese (Mn) ions from one side of a membrane to the other." [GOC:dgf] xref: MetaCyc:RXN0-16 -xref: RHEA:28699 intersection_of: GO:0015075 ! monoatomic ion transmembrane transporter activity intersection_of: has_primary_input CHEBI:29035 ! manganese(2+) relationship: part_of GO:0071421 ! manganese ion transmembrane transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0005385 @@ -52026,12 +52034,12 @@ synonym: "zinc, cadmium uptake permease activity" RELATED [] synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity" RELATED [] synonym: "zinc, iron permease activity" NARROW [] xref: MetaCyc:RXN0-12 -xref: RHEA:29351 is_a: GO:0022890 ! inorganic cation transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:29105 ! zinc(2+) relationship: part_of GO:0071577 {source="GO_REF:0000090"} ! zinc ion transmembrane transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0005388 @@ -79926,7 +79934,6 @@ def: "Enables the energy-independent facilitated diffusion of ammonium through a synonym: "ammonia transmembrane transporter activity" BROAD [] synonym: "ammonium transmembrane transporter activity" BROAD [] xref: MetaCyc:RXN-9615 -xref: RHEA:28747 xref: TC:1.A.11 intersection_of: GO:0015267 ! channel activity intersection_of: GO:0022857 ! transmembrane transporter activity @@ -79935,6 +79942,7 @@ relationship: part_of GO:0072488 {source="GO_REF:0000090"} ! ammonium transmembr property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22368" xsd:anyURI property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23129" xsd:anyURI property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0008520 @@ -109314,10 +109322,10 @@ def: "Enables the transfer of potassium ions (K+) from one side of a membrane to synonym: "potassium transporter activity" EXACT [] synonym: "potassium uptake permease activity" RELATED [] synonym: "potassium uptake transmembrane transporter activity" RELATED [] -xref: RHEA:29463 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:29103 ! potassium(1+) relationship: part_of GO:0071805 {source="GO_REF:0000090"} ! potassium ion transmembrane transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015080 @@ -109334,13 +109342,13 @@ id: GO:0015081 name: sodium ion transmembrane transporter activity namespace: molecular_function alt_id: GO:0022816 -def: "Enables the transfer of sodium ions (Na+) from one side of a membrane to the other." [GOC:ai, GOC:BHF, RHEA:34963] +def: "Enables the transfer of sodium ions (Na+) from one side of a membrane to the other." [GOC:ai, GOC:BHF] synonym: "sodium transporter activity" EXACT [] -xref: RHEA:34963 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:29101 ! sodium(1+) relationship: part_of GO:0035725 ! sodium ion transmembrane transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24076" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015083 @@ -109359,13 +109367,13 @@ relationship: part_of GO:1902602 {source="GO_REF:0000090"} ! aluminum ion transm id: GO:0015085 name: calcium ion transmembrane transporter activity namespace: molecular_function -def: "Enables the transfer of calcium (Ca) ions from one side of a membrane to the other." [GOC:dgf, RHEA:29671] +def: "Enables the transfer of calcium (Ca) ions from one side of a membrane to the other." [GOC:dgf] xref: MetaCyc:TRANS-RXN-144 -xref: RHEA:29671 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:29108 ! calcium(2+) relationship: part_of GO:0070588 ! calcium ion transmembrane transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015086 @@ -109386,11 +109394,11 @@ def: "Enables the transfer of cobalt (Co2+) ions from one side of a membrane to synonym: "cobalt, zinc uptake permease activity" RELATED [] synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity" RELATED [] xref: MetaCyc:TRANS-RXN-141A -xref: RHEA:28578 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:48828 ! cobalt(2+) relationship: part_of GO:0006824 ! cobalt ion transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015089 @@ -109438,11 +109446,11 @@ alt_id: GO:0015639 def: "Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other." [ISBN:0198506732] synonym: "ferrous iron uptake transmembrane transporter activity" RELATED [] xref: MetaCyc:TRANS-RXN-8 -xref: RHEA:28486 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:29033 ! iron(2+) relationship: part_of GO:0034755 ! iron ion transmembrane transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015094 @@ -109460,11 +109468,11 @@ name: magnesium ion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of magnesium (Mg) ions from one side of a membrane to the other." [GOC:dgf] xref: MetaCyc:TRANS-RXN-141 -xref: RHEA:29827 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:18420 ! magnesium(2+) relationship: part_of GO:1903830 ! magnesium ion transmembrane transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015096 @@ -109480,10 +109488,10 @@ id: GO:0015097 name: mercury ion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of mercury (Hg2+) ions from one side of a membrane to the other." [GOC:ai] -xref: RHEA:32815 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:16793 ! mercury(2+) relationship: part_of GO:0015694 ! mercury ion transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015098 @@ -109502,11 +109510,11 @@ namespace: molecular_function def: "Enables the transfer of nickel (Ni) cations from one side of a membrane to the other." [GOC:ai] synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity" RELATED [] xref: MetaCyc:TRANS-RXN-141B -xref: RHEA:29831 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:25516 ! nickel cation relationship: part_of GO:0035444 {source="GO_REF:0000090"} ! nickel cation transmembrane transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015100 @@ -109559,11 +109567,11 @@ name: bicarbonate transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-." [GOC:ai] synonym: "hydrogencarbonate transmembrane transporter activity" EXACT [] -xref: RHEA:28695 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:17544 ! hydrogencarbonate relationship: part_of GO:0015701 ! bicarbonate transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26780" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015107 @@ -109586,21 +109594,21 @@ synonym: "chloride ABC transporter" NARROW [] synonym: "chloride ion transmembrane transporter activity" EXACT [GOC:pr] synonym: "chloride transporting ATPase activity" NARROW [] synonym: "chloride-transporting ATPase activity" NARROW [] -xref: RHEA:29823 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:17996 ! chloride relationship: part_of GO:1902476 ! chloride transmembrane transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20821" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015109 name: chromate transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of chromate from one side of a membrane to the other. Chromate is the anion of chromic acid, H2CrO4 (aq) or CrO3." [GOC:ai] -xref: RHEA:32819 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:35404 ! chromate(2-) relationship: part_of GO:0015703 ! chromate transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015110 @@ -109624,13 +109632,13 @@ relationship: part_of GO:0015705 ! iodide transport id: GO:0015112 name: nitrate transmembrane transporter activity namespace: molecular_function -def: "Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other." [GOC:ai, RHEA:34923] +def: "Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other." [GOC:ai] synonym: "nitrite/nitrate porter activity" RELATED [] -xref: RHEA:34923 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:17632 ! nitrate relationship: part_of GO:0015706 ! nitrate transmembrane transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21337" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015113 @@ -109672,10 +109680,10 @@ namespace: molecular_function def: "Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other." [GOC:ai] synonym: "sulfate permease activity" RELATED [] synonym: "sulphate transporter activity" EXACT [] -xref: RHEA:34983 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:16189 ! sulfate relationship: part_of GO:1902358 {source="GO_REF:0000090"} ! sulfate transmembrane transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015117 @@ -109685,12 +109693,12 @@ def: "Enables the transfer of thiosulfate ions, HS2O3(1-), from one side of a me synonym: "thiosulfate permease activity" RELATED [] synonym: "thiosulphate transporter activity" EXACT [] xref: MetaCyc:TRANS-RXN-496 -xref: RHEA:32807 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:33542 ! trioxidosulfanidosulfate(1-) relationship: part_of GO:0015709 ! thiosulfate transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27324" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015119 @@ -109779,13 +109787,13 @@ relationship: part_of GO:0035429 {source="GO_REF:0000090"} ! gluconate transmemb id: GO:0015129 name: lactate transmembrane transporter activity namespace: molecular_function -def: "Enables the transfer of lactate from one side of a membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices." [GOC:ai, ISBN:0198506732, RHEA:34987] +def: "Enables the transfer of lactate from one side of a membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices." [GOC:ai, ISBN:0198506732] synonym: "monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity" RELATED [] -xref: RHEA:34987 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:24996 ! lactate relationship: part_of GO:0035873 {source="GO_REF:0000090"} ! lactate transmembrane transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24076" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015130 @@ -109860,14 +109868,14 @@ relationship: part_of GO:0015739 ! sialic acid transport id: GO:0015137 name: citrate transmembrane transporter activity namespace: molecular_function -def: "Enables the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of a membrane to the other." [GOC:ai, RHEA:33183] +def: "Enables the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of a membrane to the other." [GOC:ai] synonym: "tricarboxylate transport protein" RELATED [TC:2.A.29.7.2] -xref: RHEA:33183 xref: TC:2.A.29.7.2 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:16947 ! citrate(3-) relationship: part_of GO:0015746 ! citrate transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24076" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015138 @@ -110019,15 +110027,15 @@ id: GO:0015153 name: rhamnose transmembrane transporter activity namespace: molecular_function alt_id: GO:0033297 -def: "Enables the transfer of rhamnose from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids." [GOC:ai, GOC:mtg_transport, ISBN:0815340729, RHEA:34995] +def: "Enables the transfer of rhamnose from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "ATP-dependent rhamnose transmembrane transporter activity" NARROW [] synonym: "ATPase-coupled rhamnose transmembrane transporter activity" NARROW [] synonym: "rhamnose-transporting ATPase activity" NARROW [] -xref: RHEA:34995 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:26546 ! rhamnose relationship: part_of GO:0015762 ! rhamnose transmembrane transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17289" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015154 @@ -110421,15 +110429,15 @@ name: L-serine transmembrane transporter activity namespace: molecular_function alt_id: GO:0015511 alt_id: GO:1905361 -def: "Enables the transfer of L-serine from one side of a membrane to the other. L-serine is the L-enantiomer of 2-amino-3-hydroxypropanoic acid." [GOC:ai, GOC:jsg, GOC:mah, GOC:mtg_transport, RHEA:35031] +def: "Enables the transfer of L-serine from one side of a membrane to the other. L-serine is the L-enantiomer of 2-amino-3-hydroxypropanoic acid." [GOC:ai, GOC:jsg, GOC:mah, GOC:mtg_transport] synonym: "L-serine permease activity" RELATED [] synonym: "L-serine transporter activity" BROAD [] synonym: "serine transporter activity" BROAD [] synonym: "threonine/serine:sodium symporter activity" RELATED [] -xref: RHEA:35031 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:33384 ! L-serine zwitterion relationship: part_of GO:0015825 ! L-serine transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015195 @@ -110497,11 +110505,11 @@ namespace: molecular_function alt_id: GO:0015287 def: "Enables the transfer of urea from one side of a membrane to the other. Urea is the water soluble compound H2N-CO-NH2." [ISBN:0198506732] synonym: "urea transporter activity" BROAD [] -xref: RHEA:32799 intersection_of: GO:0005215 ! transporter activity intersection_of: has_primary_input CHEBI:16199 ! urea intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: part_of GO:0071918 {source="GO_REF:0000090"} ! urea transmembrane transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015205 @@ -110688,12 +110696,12 @@ synonym: "biotin transporter activity" RELATED [] synonym: "vitamin B7 transporter activity" RELATED [] synonym: "vitamin H transporter activity" RELATED [] xref: MetaCyc:TRANS-RXN0-240 -xref: RHEA:28458 is_a: GO:0090482 ! vitamin transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:57586 ! biotinate relationship: part_of GO:0015878 ! biotin transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI created_by: al creation_date: 2012-11-08T14:18:56Z @@ -110802,12 +110810,12 @@ synonym: "thiamin uptake transporter activity" RELATED [] synonym: "thiamine permease activity" EXACT [] synonym: "thiamine uptake transmembrane transporter activity" RELATED [] synonym: "vitamin B1 transporter activity" EXACT [] -xref: RHEA:34919 is_a: GO:0022857 ! transmembrane transporter activity is_a: GO:0090482 ! vitamin transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:26948 ! vitamin B1 relationship: part_of GO:0071934 {source="GO_REF:0000090"} ! thiamine transmembrane transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015240 @@ -110884,12 +110892,13 @@ namespace: molecular_function def: "Enables the energy-independent facilitated diffusion of water through a transmembrane aqueous pore or channel." [GOC:mtg_transport, ISBN:0815340729] synonym: "aquaporin" NARROW [] xref: MetaCyc:TRANS-RXN-145 -xref: RHEA:29667 +xref: RHEA:29667 {source="skos:broadMatch"} is_a: GO:0005372 ! water transmembrane transporter activity is_a: GO:0015267 ! channel activity intersection_of: GO:0015267 ! channel activity intersection_of: has_primary_input CHEBI:15377 ! water property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015252 @@ -110920,10 +110929,11 @@ name: glycerol channel activity namespace: molecular_function def: "Enables the energy-independent facilitated diffusion of glycerol through a transmembrane aqueous pore or channel." [GOC:mtg_transport, ISBN:0815340729] xref: MetaCyc:TRANS-RXN-131 -xref: RHEA:29675 +xref: RHEA:29675 {source="skos:broadMatch"} intersection_of: GO:0015267 ! channel activity intersection_of: has_primary_input CHEBI:17754 ! glycerol property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015255 @@ -111021,8 +111031,10 @@ id: GO:0015265 name: urea channel activity namespace: molecular_function def: "Enables the energy-independent facilitated diffusion of urea through a transmembrane aqueous pore or channel." [GOC:mtg_transport] +xref: RHEA:32799 {source="skos:broadMatch"} intersection_of: GO:0015267 ! channel activity intersection_of: has_primary_input CHEBI:16199 ! urea +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015267 @@ -113274,9 +113286,11 @@ name: maltose transporting porin activity namespace: molecular_function def: "Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. This transporter is a porin so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria." [GOC:mtg_transport] synonym: "maltoporin" EXACT [] +xref: RHEA:33171 {source="skos:broadMatch"} xref: Wikipedia:Maltoporin is_a: GO:0005363 ! maltose transmembrane transporter activity is_a: GO:0015288 ! porin activity +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015482 @@ -113452,11 +113466,11 @@ def: "Enables the transfer of formate from one side of a membrane to the other. synonym: "formate uptake permease activity" EXACT [] synonym: "formate uptake transmembrane transporter activity" RELATED [] xref: MetaCyc:TRANS-RXN-1 -xref: RHEA:29679 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:15740 ! formate relationship: part_of GO:0015724 ! formate transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015500 @@ -114024,16 +114038,16 @@ is_a: GO:0022857 ! transmembrane transporter activity id: GO:0015565 name: threonine efflux transmembrane transporter activity namespace: molecular_function -def: "Enables the transfer of threonine from the inside of the cell to the outside of the cell across a membrane." [GOC:mtg_transport, ISBN:0815340729, RHEA:35019] +def: "Enables the transfer of threonine from the inside of the cell to the outside of the cell across a membrane." [GOC:mtg_transport, ISBN:0815340729] synonym: "threonine efflux permease activity" EXACT [] synonym: "threonine export protein" RELATED [] synonym: "threonine export transporter activity" EXACT [] -xref: RHEA:35019 is_a: GO:0015195 ! L-threonine transmembrane transporter activity is_a: GO:0034639 ! L-amino acid efflux transmembrane transporter activity intersection_of: GO:0015562 ! efflux transmembrane transporter activity intersection_of: has_primary_input CHEBI:26986 ! threonine property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24076" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015566 @@ -114113,10 +114127,10 @@ namespace: molecular_function alt_id: GO:0015584 def: "Enables the transfer of trehalose from one side of a membrane to the other. Trehalose is the disaccharide alpha-D-glucopyranosyl-alpha-D-glucopyranoside that acts of a reserve carbohydrate in certain fungi, algae and lichens." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] synonym: "trehalose permease activity" EXACT [] -xref: RHEA:17629 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:27082 ! trehalose relationship: part_of GO:0015771 ! trehalose transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015575 @@ -114147,12 +114161,12 @@ id: GO:0015577 name: galactitol transmembrane transporter activity namespace: molecular_function alt_id: GO:0015588 -def: "Enables the transfer of a galactitol from one side of a membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose." [GOC:ai, GOC:mtg_transport, ISBN:0815340729, RHEA:33143] +def: "Enables the transfer of a galactitol from one side of a membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "galactitol permease activity" EXACT [] -xref: RHEA:33143 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:16813 ! galactitol relationship: part_of GO:0015796 ! galactitol transmembrane transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015578 @@ -114320,13 +114334,13 @@ relationship: part_of GO:0015748 ! organophosphate ester transport id: GO:0015606 name: spermidine transmembrane transporter activity namespace: molecular_function -def: "Enables the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of a membrane to the other." [GOC:ai, RHEA:35039] -xref: RHEA:35039 +def: "Enables the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of a membrane to the other." [GOC:ai] is_a: GO:0015203 ! polyamine transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:57834 ! spermidine(3+) relationship: part_of GO:1903711 ! spermidine transmembrane transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24076" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0015607 @@ -155714,16 +155728,20 @@ id: GO:0022818 name: sodium ion uniporter activity namespace: molecular_function def: "Catalysis of the active transport of a sodium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged." [GOC:mtg_transport, ISBN:0815340729] +xref: RHEA:34963 {source="skos:broadMatch"} intersection_of: GO:0022810 ! membrane potential driven uniporter activity intersection_of: has_primary_input CHEBI:29101 ! sodium(1+) +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0022819 name: potassium ion uniporter activity namespace: molecular_function def: "Catalysis of the active transport of a potassium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged." [GOC:mtg_transport, ISBN:0815340729] +xref: RHEA:29463 {source="skos:broadMatch"} intersection_of: GO:0022810 ! membrane potential driven uniporter activity intersection_of: has_primary_input CHEBI:29103 ! potassium(1+) +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0022821 @@ -179709,10 +179727,10 @@ name: riboflavin transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of riboflavin from one side of a membrane to the other. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins." [GOC:rn, PMID:16204239] synonym: "riboflavin transporter activity" RELATED [] -xref: RHEA:35015 intersection_of: GO:0090482 ! vitamin transmembrane transporter activity intersection_of: has_primary_input CHEBI:57986 ! riboflavin(1-) relationship: part_of GO:0032218 {source="GO_REF:0000090"} ! riboflavin transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0032218 @@ -191574,10 +191592,10 @@ namespace: molecular_function def: "Enables the transfer of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, from one side of a membrane to the other." [GOC:go_curators] synonym: "dehydroascorbate transporter activity" EXACT [] synonym: "dehydroascorbic acid transporter activity" RELATED [] -xref: RHEA:60380 intersection_of: GO:0090482 ! vitamin transmembrane transporter activity intersection_of: has_primary_input CHEBI:58070 ! dehydroascorbide(1-) relationship: part_of GO:0070837 ! dehydroascorbic acid transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0033301 @@ -200418,10 +200436,10 @@ synonym: "ATP-coupled sterol transmembrane transporter activity" RELATED [] synonym: "ATP-dependent sterol transmembrane transporter activity" RELATED [] synonym: "ATPase-coupled sterol transmembrane transporter activity" RELATED [] synonym: "sterol-transporting ATPase activity" RELATED [] -xref: RHEA:39747 {source="skos:narrowMatch"} intersection_of: GO:0140359 ! ABC-type transporter activity intersection_of: has_primary_input CHEBI:15889 ! sterol property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14793" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0034042 @@ -202275,11 +202293,11 @@ synonym: "2-aminoethanol transmembrane transporter activity" EXACT [] synonym: "ethanolamine permease activity" EXACT [] synonym: "monoethanolamine transmembrane transporter activity" EXACT [] xref: MetaCyc:TRANS-RXN0-476 -xref: RHEA:32747 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:57603 ! ethanolaminium(1+) relationship: part_of GO:0034229 ! ethanolamine transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0034229 @@ -202603,11 +202621,11 @@ name: nicotinamide riboside transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other." [GOC:se] xref: MetaCyc:TRANS-RXN0-481 -xref: RHEA:33163 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:15927 ! N-ribosylnicotinamide relationship: part_of GO:0034258 ! nicotinamide riboside transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0034258 @@ -242077,11 +242095,11 @@ name: benzoate transmembrane transporter activity namespace: molecular_function def: "Enables the directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) from one side of a membrane to the other." [GOC:jl, ISBN:0721662544] synonym: "benzoate transporter activity" RELATED [] -xref: RHEA:32811 is_a: GO:0042910 ! xenobiotic transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:16150 ! benzoate relationship: part_of GO:0042919 {source="GO_REF:0000090"} ! benzoate transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0042926 @@ -251957,15 +251975,15 @@ property_value: term_tracker_item "https://github.com/geneontology/go-ontology/i id: GO:0043879 name: glycolate transmembrane transporter activity namespace: molecular_function -def: "Enables the transfer of glycolate from one side of a membrane to the other. Glycolate is the smallest alpha-hydroxy acid (AHA)." [GOC:jl, RHEA:29447] +def: "Enables the transfer of glycolate from one side of a membrane to the other. Glycolate is the smallest alpha-hydroxy acid (AHA)." [GOC:jl] synonym: "glcA" RELATED [] synonym: "glycolate permease" RELATED [] synonym: "glycolic acid transmembrane transporter activity" EXACT [] synonym: "hydroxyacetic acid transmembrane transporter activity" EXACT [] -xref: RHEA:29447 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:29805 ! glycolate relationship: part_of GO:0097339 ! glycolate transmembrane transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0043880 @@ -317420,8 +317438,10 @@ name: galactose uniporter activity namespace: molecular_function def: "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in)." [GOC:ai, TC:2.A.1.1.6] synonym: "galactose, glucose uniporter activity" BROAD [] +xref: RHEA:34915 {source="skos:broadMatch"} is_a: GO:0005354 ! galactose transmembrane transporter activity is_a: GO:0008516 ! hexose uniporter activity +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI [Term] id: GO:0050783 @@ -357891,7 +357911,7 @@ alt_id: GO:0005288 alt_id: GO:0015181 alt_id: GO:0015598 alt_id: GO:0102022 -def: "Enables the transfer of L-arginine from one side of a membrane to the other." [GOC:dph, RHEA:32143] +def: "Enables the transfer of L-arginine from one side of a membrane to the other." [GOC:dph] synonym: "arginine permease activity" BROAD [] synonym: "arginine porter activity" NARROW [] synonym: "arginine transmembrane transporter activity" EXACT [] @@ -357902,13 +357922,13 @@ synonym: "histidine/arginine/lysine/ornithine porter activity" NARROW [] synonym: "L-arginine transporter activity" EXACT [] synonym: "L-arginine-importing ATPase activity" NARROW [] xref: MetaCyc:RXN66-448 -xref: RHEA:32143 is_a: GO:0015174 ! basic amino acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:32682 ! L-argininium(1+) relationship: part_of GO:1903826 ! L-arginine transmembrane transport property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22228" xsd:anyURI property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26941" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI created_by: dph creation_date: 2012-09-25T08:37:29Z @@ -453939,12 +453959,12 @@ creation_date: 2020-06-29T08:59:24Z id: GO:0140485 name: 5-aminolevulinic acid transmembrane transporter activity namespace: molecular_function -def: "Enables the transfer of 5-aminolevulinic acid from one side of a membrane to the other." [PMID:31989647, RHEA:64816] -xref: RHEA:64816 +def: "Enables the transfer of 5-aminolevulinic acid from one side of a membrane to the other." [PMID:31989647] intersection_of: GO:0005215 ! transporter activity intersection_of: has_primary_input CHEBI:356416 ! 5-ammoniolevulinate intersection_of: results_in_transport_across GO:0016020 ! membrane property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19527" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI created_by: pg creation_date: 2020-06-29T09:02:26Z @@ -457325,9 +457345,11 @@ id: GO:0140787 name: phosphate ion uniporter activity namespace: molecular_function def: "Catalysis of the active transport of a phosphate ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged." [PMID:29642010] +xref: RHEA:32823 {source="skos:broadMatch"} intersection_of: GO:0022810 ! membrane potential driven uniporter activity intersection_of: has_primary_input CHEBI:43474 ! hydrogenphosphate property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23132" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI created_by: pg creation_date: 2022-04-05T07:42:20Z @@ -464848,10 +464870,11 @@ id: GO:0160081 name: iodide channel activity namespace: molecular_function def: "Enables the energy-independent facilitated diffusion of iodide through a transmembrane aqueous pore or channel." [PMID:34910516] -xref: RHEA:66324 +xref: RHEA:66324 {source="skos:broadMatch"} intersection_of: GO:0015267 ! channel activity intersection_of: has_primary_input CHEBI:16382 ! iodide property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25578" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI created_by: rynl creation_date: 2023-07-12T18:10:32Z @@ -465389,10 +465412,12 @@ name: bicarbonate channel activity namespace: molecular_function def: "Enables the energy-independent facilitated diffusion of bicarbonate through a transmembrane aqueous pore or channel." [PMID:18400985] synonym: "hydrogencarbonate channel activity" EXACT [] +xref: RHEA:28695 {source="skos:broadMatch"} intersection_of: GO:0015267 ! channel activity intersection_of: has_primary_input CHEBI:17544 ! hydrogencarbonate property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26601" xsd:anyURI property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26780" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI created_by: rynl creation_date: 2023-12-13T00:09:44Z @@ -466336,9 +466361,9 @@ id: GO:0170003 name: heme B transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of heme B from one side of a membrane to the other." [PMID:15369674, PMID:20610401, PMID:32121449, PMID:9657107] -xref: RHEA:75443 is_a: GO:0015232 ! heme transmembrane transporter activity property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24973" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI created_by: ew creation_date: 2023-05-31T17:45:03Z @@ -490037,10 +490062,10 @@ id: GO:1901235 name: (R)-carnitine transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of (R)-carnitine from one side of a membrane to the other." [GOC:TermGenie, PMID:16365042, PMID:20357772, PMID:20829798] -xref: RHEA:34959 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:16347 ! (R)-carnitine relationship: part_of GO:1902270 {source="GO_REF:0000090"} ! (R)-carnitine transmembrane transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI created_by: jl creation_date: 2012-08-07T14:46:17Z @@ -490049,9 +490074,9 @@ id: GO:1901236 name: 4-(trimethylammonio)butanoate transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of 4-(trimethylammonio)butanoate from one side of a membrane to the other." [GOC:TermGenie, PMID:16952940, PMID:21784948] -xref: RHEA:32835 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:16244 ! 4-(trimethylammonio)butanoate +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI created_by: jl creation_date: 2012-08-07T14:46:52Z @@ -490080,10 +490105,10 @@ namespace: molecular_function alt_id: GO:1901549 def: "Enables the transfer of malonate(1-) from one side of a membrane to the other." [GOC:TermGenie, PMID:9128730, PMID:9573154] synonym: "malonic acid uptake transmembrane transporter activity" RELATED [] -xref: RHEA:33115 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:15792 ! malonate(2-) relationship: part_of GO:1901553 ! malonic acid transmembrane transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI created_by: al creation_date: 2012-08-07T15:09:02Z @@ -490092,9 +490117,9 @@ id: GO:1901241 name: 4-hydroxyphenylacetate transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of 4-hydroxyphenylacetate from one side of a membrane to the other." [GOC:TermGenie, PMID:9315705] -xref: RHEA:33175 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:48999 ! 4-hydroxyphenylacetate +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI created_by: jl creation_date: 2012-08-07T15:09:49Z @@ -494198,11 +494223,11 @@ creation_date: 2012-10-04T23:21:10Z id: GO:1901480 name: oleate transmembrane transporter activity namespace: molecular_function -def: "Enables the transfer of oleate from one side of a membrane to the other." [GOC:TermGenie, PMID:19493158, RHEA:33655] +def: "Enables the transfer of oleate from one side of a membrane to the other." [GOC:TermGenie, PMID:19493158] synonym: "oleate transporter activity" RELATED [] -xref: RHEA:33655 intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:30823 ! oleate +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27521" xsd:anyURI created_by: ab creation_date: 2012-10-07T17:11:56Z