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XEC+Orf1a:A599T+S:T572I(54 seqs, >10 places) #2803

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xz-keg opened this issue Oct 12, 2024 · 16 comments
Open

XEC+Orf1a:A599T+S:T572I(54 seqs, >10 places) #2803

xz-keg opened this issue Oct 12, 2024 · 16 comments

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@xz-keg
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xz-keg commented Oct 12, 2024

S:T572I is the top mutation predicted by the mutation GPT on XEC backbone, and there are really multiple S:T572I lineages emerging.

From sars-cov-2-variants/lineage-proposals#2087
XEC+G2060A(Orf1a:A599T)+C23277T(S:T572I)

GISAID query: G2060A, C23277T,C18657T,-14106,-G2272A,-24034 (may include more -s as convergent going on)
No. of seqs: 18(Australia 10(SA,QLD,NSW), Netherlands 1 Italy 1 Spain 1 Sweden 2 UK 1 USA 2(GBW from New Zealand))

First: EPI_ISL_19448172, Italy, 2024-8-25
Latest: EPI_ISL_19472822, USA from New Zealand, 2024-9-30

usher

image

@FedeGueli
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FedeGueli commented Oct 12, 2024

One of the fastest lets see what it will do outside Australia

@FedeGueli
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20 with G2060A, C23277T,C18657T,-14106,-G2272A but one sample is ENV/Germany and it seems a mix of multiple lineages

@xz-keg xz-keg changed the title XEC+Orf1a:A599T+S:T572I(18 seqs, 9 places) XEC+Orf1a:A599T+S:T572I(19 seqs, 10 places) Oct 15, 2024
@FedeGueli
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20 Netherlands

@xz-keg xz-keg changed the title XEC+Orf1a:A599T+S:T572I(19 seqs, 10 places) XEC+Orf1a:A599T+S:T572I(20 seqs, 10 places) Oct 15, 2024
@xz-keg
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xz-keg commented Oct 17, 2024

+2 Australia-WA

@xz-keg xz-keg changed the title XEC+Orf1a:A599T+S:T572I(20 seqs, 10 places) XEC+Orf1a:A599T+S:T572I(23 seqs, >10 places) Oct 17, 2024
@FedeGueli
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tenth sample was from California

@xz-keg xz-keg changed the title XEC+Orf1a:A599T+S:T572I(23 seqs, >10 places) XEC+Orf1a:A599T+S:T572I(24 seqs, >10 places) Oct 19, 2024
@FedeGueli
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26, NZL

@xz-keg xz-keg changed the title XEC+Orf1a:A599T+S:T572I(24 seqs, >10 places) XEC+Orf1a:A599T+S:T572I(25 seqs, >10 places) Oct 21, 2024
@FedeGueli
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29

@FedeGueli
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query changed

@xz-keg
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xz-keg commented Oct 22, 2024

query changed

to what?

@xz-keg xz-keg changed the title XEC+Orf1a:A599T+S:T572I(25 seqs, >10 places) XEC+Orf1a:A599T+S:T572I(29 seqs, >10 places) Oct 22, 2024
@FedeGueli
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query changed

to what?

in comparison to the previous one the query has one more -s, or just i forgot to add it in the previous step.

@xz-keg
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xz-keg commented Oct 23, 2024

32, Germany

@xz-keg xz-keg changed the title XEC+Orf1a:A599T+S:T572I(29 seqs, >10 places) XEC+Orf1a:A599T+S:T572I(32 seqs, >10 places) Oct 23, 2024
@xz-keg xz-keg changed the title XEC+Orf1a:A599T+S:T572I(32 seqs, >10 places) XEC+Orf1a:A599T+S:T572I(36 seqs, >10 places) Oct 24, 2024
@xz-keg
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xz-keg commented Oct 24, 2024

image

Decent 20% advantage than XEC

@FedeGueli
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@FedeGueli
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37

@xz-keg xz-keg changed the title XEC+Orf1a:A599T+S:T572I(36 seqs, >10 places) XEC+Orf1a:A599T+S:T572I(38 seqs, >10 places) Oct 25, 2024
@xz-keg
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xz-keg commented Oct 25, 2024

also in Australia-WA

@xz-keg xz-keg changed the title XEC+Orf1a:A599T+S:T572I(38 seqs, >10 places) XEC+Orf1a:A599T+S:T572I(42 seqs, >10 places) Oct 27, 2024
@xz-keg
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xz-keg commented Oct 30, 2024

54, Slovenia

@xz-keg xz-keg changed the title XEC+Orf1a:A599T+S:T572I(42 seqs, >10 places) XEC+Orf1a:A599T+S:T572I(54 seqs, >10 places) Oct 30, 2024
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