- Allows fitting the same model to multiple samples
- Two-Compartments with intrinsic clearance and metabolites added
- Two-Compartments with autoinduction added
- Allometric scaling can now be estimated and applied
- Labels can be rewritten and several labels added at the same time
- Infusions are now computed more accurately
- MonoCompartment with intrinsic clearance added
- Two-Compartments with intrinsic clearance added
- Internal structure redesigned to support simultaneous intravenous and extravascular doses
- Bioavailability and lag time of drug sources can now be estimated
- Pharmacodynamics models added
- More Pharmacokinetics models added
- Administrative tasks: importing/exporting experiments, filter and join samples, filter and drop measurements, creating and merging labels, calculating cumulated dose, changing units, scaling doses
- Non-compartmental PK: fitting exponentials, calculating elimination and absorption rates, intravenous and extra-vascular NCA,
- Compartmental PK: monocompartmental (iv and ev of orders 0, 1 and mixed; iv and order 1 ev with urine data), two-compartments (iv and ev of orders 0 and 1)
- Population PK: Bootstrapping and managing populations (merging and filtering)
- Simulating any dosing regime in an individual or population
- Simulating and fitting any generic PD profile
- PBPK: Simulating the liver flow
- Statistical tests on PKPD parameters, regression, and statistical summary