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Ensure that FixVariantCollisions works on chrY, chrX, chrM #26

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fabio-cunial opened this issue Aug 13, 2024 · 1 comment
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Ensure that FixVariantCollisions works on chrY, chrX, chrM #26

fabio-cunial opened this issue Aug 13, 2024 · 1 comment
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@fabio-cunial
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Currently it works only if the GTs on such chromosomes have the usual format A/B. But this might not be the case.

@fabio-cunial fabio-cunial self-assigned this Aug 13, 2024
@samuelklee
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ChrX is higher priority than chrY or chrM. Until recently, PanGenie was only run on 1-22 + X, so that's what we've been doing for KAGE+GLIMPSE. I believe the unreleased HGSVC3+HPRC PanGenie run does include Y, but it looks like they just hacked the calls in male samples to be homozygous on both X and Y: https://ftp.1000genomes.ebi.ac.uk/vol1/ftp/data_collections/HGSVC3/working/20240716_PanGenie-genotypes/20240716_PanGenie-genotypes_README.txt

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