Readme.md

Transkingdom multi-omic dysbiosis in metabolic dysfunction-associated steatotic liver disease (MASLD)

Description

This repository contains the analysis programs used for the study that delve into how the gut microbiome is altered in the metabolic dysfunction-associated steatotic liver disease (MASLD) among 713 participants (211 MASLD cases) in Micro-N (nested within the Nurses' Health Study II).

Included scripts

• alphadiversity_species.R
• pcoa_species_mbx.R
• permanova_species_mbx_virome.R
• table1.R
• figure1b_heatmaps.R
• figure2_maaslin_species.R
• figure3_functional_analysis.R
• figure4_maaslin_mbx.R
• figure5_maaslin_virome.R
• figure6_random_forest.R
• extendeddatafig2b.R

Data source

Data could be found here:

• BIOM-Mass under project MLSC.

Citation