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Question about Main figure 3A in paper #309

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yuling999666 opened this issue Jan 18, 2025 · 2 comments
Open

Question about Main figure 3A in paper #309

yuling999666 opened this issue Jan 18, 2025 · 2 comments

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@yuling999666
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Hi @YifanLu2000, for benchmark of Merfish Hemibrain in figure 3A, did you use non-rigid alignment? I have checked the code below, I think the answer is yes? Thank you !

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@YifanLu2000
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Hi @yuling999666, by default, Spateo uses non-rigid transformations during the optimization process to ensure more accurate correspondence calculations. However, when computing the final spatial transformations, Spateo behaves differently depending on the mode:

  • In the 'SN-S' mode, Spateo returns results with only rigid transformations, i.e., rotation and translation.
  • In the 'SN-N' mode, Spateo returns results with both rigid and non-rigid transformations.

In our benchmark using public datasets, we use 'SN-S' mode to preserve the original topological structure of the data.

@yuling999666
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Hi @YifanLu2000 , thank you for your quick response. Got it. It really helps!

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