M_Gene.py

##############################
# import
##############################
import wx

import GUI_Gene

##############################
# GUI的函数桥接
##############################


class CalcFrame(GUI_Gene.Main):
	def __init__(self, parent):
		# 定义主函数
		GUI_Gene.Main.__init__(self, parent)

	def Covid19(self, event):
		self.m_bpButton1.Show(False)
		self.m_bpButton2.Show(False)
		self.m_bpButton3.Show(False)
		self.m_bpButton4.Show(False)

		self.Recommend.Show(False)
		self.space1.Show(False)
		self.space2.Show(False)
		self.Screach.Show(False)

		self.F1.Show(False)
		self.F2.Show(False)
		self.F3.Show(False)
		self.F4.Show(False)
		######################################
		self.Show1.Show(True)
		self.Tip.SetLabel("Covid19-RNA")
		self.Tip.Show(True)
		self.Show2.Show(True)
		self.Tip2.SetLabel("protein")
		self.Tip2.Show(True)

		self.SetSize(501, 400)  ##通过改变窗口大小来刷新界面
		self.SetSize(500, 400)

		f = open(".\DATA\Gene\Covid19-RNA\RNA.txt", mode="r", encoding="utf-8")
		data = f.read()
		self.Show1.SetValue(str(data))
		self.Show2.SetValue(str(translate_rna(data)))
		f.close()

	def Close(self, event):
		try:
			if app.GetAppName() != '_core.cp38-win_amd64':
				self.Destroy()
		except:
			self.Hide()


##############################
# 主函数
##############################


def main():
	global app
	app = wx.App(False)
	frame = CalcFrame(None)
	frame.Show(True)
	app.MainLoop()


def translate_rna(sequence):
	# 密码子表
	codonTable = {
		"AUA": "I",
		"AUC": "I",
		"AUU": "I",
		"AUG": "M",
		"ACA": "T",
		"ACC": "T",
		"ACG": "T",
		"ACU": "T",
		"AAC": "N",
		"AAU": "N",
		"AAA": "K",
		"AAG": "K",
		"AGC": "S",
		"AGU": "S",
		"AGA": "R",
		"AGG": "R",
		"CUA": "L",
		"CUC": "L",
		"CUG": "L",
		"CUU": "L",
		"CCA": "P",
		"CCC": "P",
		"CCG": "P",
		"CCU": "P",
		"CAC": "H",
		"CAU": "H",
		"CAA": "Q",
		"CAG": "Q",
		"CGA": "R",
		"CGC": "R",
		"CGG": "R",
		"CGU": "R",
		"GUA": "V",
		"GUC": "V",
		"GUG": "V",
		"GUU": "V",
		"GCA": "A",
		"GCC": "A",
		"GCG": "A",
		"GCU": "A",
		"GAC": "D",
		"GAU": "D",
		"GAA": "E",
		"GAG": "E",
		"GGA": "G",
		"GGC": "G",
		"GGG": "G",
		"GGU": "G",
		"UCA": "S",
		"UCC": "S",
		"UCG": "S",
		"UCU": "S",
		"UUC": "F",
		"UUU": "F",
		"UUA": "L",
		"UUG": "L",
		"UAC": "Y",
		"UAU": "Y",
		"UAA": "",
		"UAG": "",
		"UGC": "C",
		"UGU": "C",
		"UGA": "",
		"UGG": "W",
	}
	proteinsequence = ""
	# 3个3个取
	for n in range(0, len(sequence), 3):
		if sequence[n : n + 3] in codonTable.keys():
			# 把匹配到的字典的键值加入到蛋白质字符窜
			proteinsequence += codonTable[sequence[n : n + 3]]
	return proteinsequence


if __name__ == "__main__":
	main()