diff --git a/.github/workflows/cron.yml b/.github/workflows/cron.yml
index 6732ab7256..516e2d4743 100644
--- a/.github/workflows/cron.yml
+++ b/.github/workflows/cron.yml
@@ -16,7 +16,8 @@ jobs:
           - "PT110+CUDA113"
           - "PT113+CUDA118"
           - "PT210+CUDA121"
-          - "PTLATEST+CUDA124"
+          - "PT240+CUDA126"
+          - "PTLATEST+CUDA126"
         include:
           # https://docs.nvidia.com/deeplearning/frameworks/pytorch-release-notes
           - environment: PT110+CUDA113
@@ -28,9 +29,12 @@ jobs:
           - environment: PT210+CUDA121
             pytorch: "pytorch==2.1.0 torchvision==0.16.0 --extra-index-url https://download.pytorch.org/whl/cu121"
             base: "nvcr.io/nvidia/pytorch:23.08-py3"  # CUDA 12.1
-          - environment: PTLATEST+CUDA124
+          - environment: PT240+CUDA126
+            pytorch: "pytorch==2.4.0 torchvision==0.19.0 --extra-index-url https://download.pytorch.org/whl/cu121"
+            base: "nvcr.io/nvidia/pytorch:24.08-py3"  # CUDA 12.6
+          - environment: PTLATEST+CUDA126
             pytorch: "-U torch torchvision --extra-index-url https://download.pytorch.org/whl/cu121"
-            base: "nvcr.io/nvidia/pytorch:24.08-py3"  # CUDA 12.4
+            base: "nvcr.io/nvidia/pytorch:24.10-py3"  # CUDA 12.6
     container:
       image: ${{ matrix.base }}
       options: "--gpus all"
@@ -80,7 +84,7 @@ jobs:
     if: github.repository == 'Project-MONAI/MONAI'
     strategy:
       matrix:
-        container: ["pytorch:23.08", "pytorch:24.08"]
+        container: ["pytorch:23.08", "pytorch:24.08", "pytorch:24.10"]
     container:
       image: nvcr.io/nvidia/${{ matrix.container }}-py3  # testing with the latest pytorch base image
       options: "--gpus all"
@@ -129,7 +133,7 @@ jobs:
     if: github.repository == 'Project-MONAI/MONAI'
     strategy:
       matrix:
-        container: ["pytorch:24.08"]
+        container: ["pytorch:24.10"]
     container:
       image: nvcr.io/nvidia/${{ matrix.container }}-py3  # testing with the latest pytorch base image
       options: "--gpus all"
@@ -233,7 +237,7 @@ jobs:
     if: github.repository == 'Project-MONAI/MONAI'
     needs: cron-gpu  # so that monai itself is verified first
     container:
-      image: nvcr.io/nvidia/pytorch:24.08-py3  # testing with the latest pytorch base image
+      image: nvcr.io/nvidia/pytorch:24.10-py3  # testing with the latest pytorch base image
       options: "--gpus all --ipc=host"
     runs-on: [self-hosted, linux, x64, integration]
     steps:
diff --git a/Dockerfile b/Dockerfile
index e45932c6bb..5fcfcf274d 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -11,7 +11,7 @@
 
 # To build with a different base image
 # please run `docker build` using the `--build-arg PYTORCH_IMAGE=...` flag.
-ARG PYTORCH_IMAGE=nvcr.io/nvidia/pytorch:24.08-py3
+ARG PYTORCH_IMAGE=nvcr.io/nvidia/pytorch:24.10-py3
 FROM ${PYTORCH_IMAGE}
 
 LABEL maintainer="monai.contact@gmail.com"
diff --git a/tests/test_trt_compile.py b/tests/test_trt_compile.py
index 5a56f0e4a2..6df5d520bd 100644
--- a/tests/test_trt_compile.py
+++ b/tests/test_trt_compile.py
@@ -46,7 +46,7 @@ def tearDown(self):
         if current_device != self.gpu_device:
             torch.cuda.set_device(self.gpu_device)
 
-    @SkipIfAtLeastPyTorchVersion((2, 5, 0))
+    @SkipIfAtLeastPyTorchVersion((2, 4, 1))
     def test_handler(self):
         from ignite.engine import Engine