diff --git a/build_scripts/build_usd.py b/build_scripts/build_usd.py
index 8b0ddf5f81..4cb4f0bcb6 100644
--- a/build_scripts/build_usd.py
+++ b/build_scripts/build_usd.py
@@ -1356,8 +1356,8 @@ def InstallOpenVDB(context, force, buildArgs):
 
         # Make sure to use boost installed by the build script and not any
         # system installed boost
-        extraArgs.append('-DBoost_NO_BOOST_CMAKE=On')
-        extraArgs.append('-DBoost_NO_SYSTEM_PATHS=True')
+        extraArgs.append('-DBoost_NO_BOOST_CMAKE=OFF')
+        extraArgs.append('-DBoost_NO_SYSTEM_PATHS=ON')
 
         extraArgs.append('-DBLOSC_ROOT="{instDir}"'
                          .format(instDir=context.instDir))
@@ -1410,8 +1410,8 @@ def InstallOpenImageIO(context, force, buildArgs):
 
         # Make sure to use boost installed by the build script and not any
         # system installed boost
-        extraArgs.append('-DBoost_NO_BOOST_CMAKE=On')
-        extraArgs.append('-DBoost_NO_SYSTEM_PATHS=True')
+        extraArgs.append('-DBoost_NO_BOOST_CMAKE=OFF')
+        extraArgs.append('-DBoost_NO_SYSTEM_PATHS=ON')
 
         # OpenImageIO 2.3.5 changed the default postfix for debug library
         # names from "" to "_d". USD's build system currently does not support
@@ -1870,8 +1870,9 @@ def InstallUSD(context, force, buildArgs):
 
         # Make sure to use boost installed by the build script and not any
         # system installed boost
-        extraArgs.append('-DBoost_NO_BOOST_CMAKE=On')
-        extraArgs.append('-DBoost_NO_SYSTEM_PATHS=True')
+        extraArgs.append('-DBoost_NO_BOOST_CMAKE=OFF')
+        extraArgs.append('-DBoost_NO_SYSTEM_PATHS=ON')
+
         extraArgs += buildArgs
 
         RunCMake(context, force, extraArgs)