diff --git a/main.go b/main.go
index 6e440c07..b312c21a 100644
--- a/main.go
+++ b/main.go
@@ -364,7 +364,8 @@ func findAllLockfiles(r *reporter.Reporter, pathsToCheck []string, parseAs strin
 					return false
 				}
 
-				if strings.HasSuffix(string(path), "/node_modules") {
+				if strings.HasSuffix(string(path), "/node_modules") ||
+					strings.HasSuffix(string(path), "/site-packages") {
 					paths = append(paths, string(path))
 
 					return false
@@ -422,6 +423,16 @@ func parseLockfile(pathToLock string, args []string, img *image.Image) (lockfile
 			return l, err
 		}
 
+		if isPathTo(pathToLock, "site-packages") {
+			l, err := lockfile.WalkPythonSitePackagesInImage(*img, pathToLock)
+
+			if err != nil {
+				err = fmt.Errorf("%w", err)
+			}
+
+			return l, err
+		}
+
 		if pathToLock == "/lib/apk/db/installed" {
 			r, err := img.OpenPathFromSquash(file.Path(pathToLock))
 			if err != nil {
diff --git a/pkg/lockfile/walk-python-site-packages.go b/pkg/lockfile/walk-python-site-packages.go
index ce82cf73..fbd24040 100644
--- a/pkg/lockfile/walk-python-site-packages.go
+++ b/pkg/lockfile/walk-python-site-packages.go
@@ -3,6 +3,10 @@ package lockfile
 import (
 	"bufio"
 	"fmt"
+	"github.com/anchore/stereoscope/pkg/file"
+	"github.com/anchore/stereoscope/pkg/filetree"
+	"github.com/anchore/stereoscope/pkg/filetree/filenode"
+	"github.com/anchore/stereoscope/pkg/image"
 	"io"
 	"io/fs"
 	"os"
@@ -49,6 +53,88 @@ func readPythonSitePackageMetadata(r io.Reader) (name, version string, err error
 	return name, version, err
 }
 
+func WalkPythonSitePackagesInImage(img image.Image, pathToPythonSitePackages string) (Lockfile, error) {
+	var packages []PackageDetails
+
+	err := img.SquashedTree().Walk(
+		func(path file.Path, f filenode.FileNode) error {
+			metadataFile := ""
+
+			if strings.HasSuffix(string(path), ".dist-info") {
+				metadataFile = "METADATA"
+			}
+
+			if strings.HasSuffix(string(path), ".egg-info") {
+				metadataFile = "PKG-INFO"
+			}
+
+			if metadataFile != "" {
+				r, err := img.OpenPathFromSquash(path + file.Path("/"+metadataFile))
+
+				if err != nil {
+					_, _ = fmt.Fprintf(os.Stderr, "%v\n", err)
+
+					return nil
+				}
+
+				name, version, err := readPythonSitePackageMetadata(r)
+
+				if err != nil {
+					_, _ = fmt.Fprintf(os.Stderr, "%v\n", err)
+
+					return nil
+				}
+
+				packages = append(packages, PackageDetails{
+					Name:      name,
+					Version:   version,
+					Commit:    "",
+					Ecosystem: PipEcosystem,
+					CompareAs: PipEcosystem,
+				})
+
+				return nil
+			}
+
+			return nil
+		},
+		&filetree.WalkConditions{
+			ShouldVisit: func(path file.Path, node filenode.FileNode) bool {
+				// we only want to visit the node if:
+				//   1. it is a directory
+				//   2. it is within the given site-packages directory
+				return node.FileType == file.TypeDirectory &&
+					strings.HasPrefix(string(path), pathToPythonSitePackages)
+			},
+			ShouldContinueBranch: func(path file.Path, node filenode.FileNode) bool {
+				// We want to avoid any symlinks as they could be cyclical, and they should
+				// be safe to skip since we should end up walking their targets eventually
+				if IsSymlink(path, node) {
+					return false
+				}
+
+				// we don't actually need to explore these directories, as site-packages is a flat module tree,
+				// and we can access the metadata file within the directory when we visit it
+				return !strings.HasSuffix(string(path), ".dist-info") && !strings.HasSuffix(string(path), ".egg-info")
+			},
+		},
+	)
+
+	sort.Slice(packages, func(i, j int) bool {
+		if packages[i].Name == packages[j].Name {
+			return packages[i].Version < packages[j].Version
+		}
+
+		return packages[i].Name < packages[j].Name
+	})
+
+	return Lockfile{
+		FilePath: pathToPythonSitePackages,
+		ParsedAs: "site-packages",
+		Packages: packages,
+	}, err
+}
+
 func WalkPythonSitePackages(pathToPythonSitePackages string) (Lockfile, error) {
 	var packages []PackageDetails