diff --git a/docker/Dockerfile b/docker/Dockerfile
index 4a7a45bb..02181791 100644
--- a/docker/Dockerfile
+++ b/docker/Dockerfile
@@ -60,7 +60,7 @@ RUN \
 RUN \
     build_deps="automake bzip2-dev cyrus-sasl-dev git g++ gcc libffi-dev libjpeg-turbo-dev libwebp-dev libxml2-dev libxslt-dev make musl-dev openjpeg-dev openldap-dev openssl-dev pcre-dev python3-dev postgresql-dev su-exec tiff-dev zlib-dev " &&\
     run_deps="curl krb5-libs libgcc libjpeg-turbo libldap libpq libsasl libstdc++ libwebp libxml2 libxslt netcat-openbsd openjpeg python3 rsync tiff tidyhtml" &&\
-    py_deps="py3-numpy py3-pandas py3-pillow py3-psycopg2" &&\
+    py_deps="py3-numpy py3-pandas py3-pillow py3-psycopg2 py3-biopython" &&\
     /sbin/apk update --quiet &&\
     /sbin/apk add --no-progress --quiet --virtual /edrn-build $build_deps &&\
     /sbin/apk add --no-progress --quiet $run_deps &&\
@@ -74,6 +74,7 @@ RUN [ "`/usr/bin/python3 -c 'import numpy; print(numpy.__version__)'`" = "1.24.4
 RUN [ "`/usr/bin/python3 -c 'import pandas; print(pandas.__version__)'`" = "1.5.3" ]
 RUN [ "`/usr/bin/python3 -c 'import PIL; print(PIL.__version__)'`" = "9.5.0" ]
 RUN [ "`/usr/bin/python3 -c 'import psycopg2; print(psycopg2.__version__)'`" = "2.9.6 (dt dec pq3 ext lo64)" ]
+RUN [ "`/usr/bin/python3 -c 'import Bio; print(Bio.__version__)'`" = "1.81" ]
 
 RUN \
     : See https://github.com/python-ldap/python-ldap/issues/432 for workaround to Python LDAP vs OpenLDAP 2.5 issue &&\
diff --git a/src/eke.biomarkers/setup.cfg b/src/eke.biomarkers/setup.cfg
index 60a2abf2..8b3e7e43 100644
--- a/src/eke.biomarkers/setup.cfg
+++ b/src/eke.biomarkers/setup.cfg
@@ -21,7 +21,7 @@ install_requires =
     eke.knowledge
     edrnsite.content
     edrn.auth
-    biopython          ~= 1.79
+    biopython          == 1.81    # Must mathc py3-biopython package in Dockerfile
     django             <  5
     django_plotly_dash == 1.7.1
     numpy              == 1.24.4  # Must match py3-numpy package in Dockerfile
diff --git a/src/eke.knowledge/setup.cfg b/src/eke.knowledge/setup.cfg
index e3fe6383..ff001aa0 100644
--- a/src/eke.knowledge/setup.cfg
+++ b/src/eke.knowledge/setup.cfg
@@ -22,7 +22,7 @@ install_requires =
     edrnsite.controls
     edrn.collabgroups
     eke.geocoding
-    biopython                       ~= 1.79
+    biopython                       == 1.81    # Must match py3-biopython package in Dockerfile
     boto3                           ~= 1.24.75
     celery                          ~= 5.2.7
     dash-dangerously-set-inner-html ~= 0.0.2