DESCRIPTION

Package: drugfindR
Title: Investigate iLINCS for candidate repurposable drugs
Version: 0.99.1014
Authors@R: c(
    person(given = c("Ali", "Sajid"),
           family = "Imami",
           role = c("aut", "cre"),
           email = "Ali.Sajid.Imami@gmail.com",
           comment = c(ORCID = "0000-0003-3684-3539")),
    person(given = c("Smita"),
            family = "Sahay",
            role = c("aut"),
            email = "Smita.Sahay@rockets.utoledo.edu",
            comment = c(ORCID = "0009-0003-4377-8963")),
    person(given = c("Justin", "Fortune"),
           family = "Creeden",
           role = c("aut"),
           email = "Justin.Creeden@rockets.utoledo.edu",
           comment = c(ORCID = "0000-0003-3123-8401")),
    )
Description: This package provides a convenient way to access the
    LINCS Signatures available in the iLINCS database. These signatures include
    Consensus Gene Knockdown Signatures, Gene Overexpression signatures and
    Chemical Perturbagen Signatures. It also provides a way to enter your own
    transcriptomic signatures and identify concordant and discordant signatures
    in the LINCS database.
License: GPL-3 + file LICENSE
Encoding: UTF-8
URL: https://github.com/CogDisResLab/drugfindR
BugReports: https://github.com/CogDisResLab/drugfindR/issues
LazyData: false
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2
biocViews: FunctionalPrediction, DifferentialExpression, GeneSetEnrichment
Imports:
    magrittr,
    tibble,
    rlang,
    dplyr,
    purrr,
    readr,
    stringr,
    stats,
    lifecycle,
    S4Vectors,
    httr2,
    curl
Depends:
    R (>= 4.4.0)
Suggests:
    AnnotationDbi,
    BiocStyle,
    biocthis,
    codemetar,
    devtools,
    knitr,
    rmarkdown,
    testthat (>= 3.0.0),
    tidyverse,
    usethis,
    vcr (>= 0.6.0),
    webmockr
Config/testthat/edition: 3
Config/testthat/parallel: true
VignetteBuilder: knitr
X-schema.org-applicationCategory: Genomics
X-schema.org-keywords: LINCS, iLINCS, drug repurposing, drug discovery,
    transcriptomics, gene expression, gene knockdown, gene overexpression,
    chemical perturbagen, drugfindR
X-schema.org-isPartOf: https://bioconductor.org
Collate:
    'utilities.R'
    'consensusConcordants.R'
    'drugfindR-package.R'
    'filterSignature.R'
    'getConcordants.R'
    'getSignature.R'
    'prepareSignature.R'
    'investigateSignature.R'
    'investigateTarget.R'