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sbo.sql
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INSERT INTO soterms (id, name, definition) VALUES ('0000000', 'systems biology representation', 'Representation of an entity used in a systems biology knowledge reconstruction, such as a model, pathway, network." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000001', 'rate law', 'mathematical description that relates quantities of reactants to the reaction velocity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000002', 'quantitative systems description parameter', 'A numerical value that defines certain characteristics of systems or system functions. It may be part of a calculation, but its value is not determined by the form of the equation itself, and may be arbitrarily assigned." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000003', 'participant role', 'The function of a physical or conceptual entity, that is its role, in the execution of an event or process." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000004', 'modelling framework', 'Set of assumptions that underlay a mathematical description." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000005', 'obsolete mathematical expression', 'The description of a system in mathematical terms." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000006', 'obsolete parameter', 'A numerical value that represents the amount of some entity, process or mathematical function of the system." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000007', 'obsolete participant type', 'The kind of entity involved in some process, action or reaction in the system. This may be enzyme, simple chemical, etc.." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000008', 'obsolete modelling framework', 'Basic assumptions that underlie a mathematical model." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000009', 'kinetic constant', 'Numerical parameter that quantifies the velocity of a chemical reaction." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000010', 'reactant', 'Substance consumed by a chemical reaction. Reactants react with each other to form the products of a chemical reaction. In a chemical equation the Reactants are the elements or compounds on the left hand side of the reaction equation. A reactant can be consumed and produced by the same reaction, its global quantity remaining unchanged." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000011', 'product', 'Substance that is produced in a reaction. In a chemical\nequation the Products are the elements or compounds on the right hand side\nof the reaction equation. A product can be produced and consumed by the\nsame reaction, its global quantity remaining unchanged." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000012', 'mass action rate law', 'The Law of Mass Action, first expressed by Waage and Guldberg in 1864 (Waage, P.; Guldberg, C. M. Forhandlinger: Videnskabs-Selskabet i Christiana 1864, 35) states that the speed of a chemical reaction is proportional to the quantity of the reacting substances. More formally, the change of a product quantity is proportional to the product of reactant activities. In the case of a reaction occurring in a gas phase, the activities are equal to the partial pressures. In the case of a well-stirred aqueous medium, the activities are equal to the concentrations. In the case of discrete kinetic description, the quantity are expressed in number of molecules and the relevant volume are implicitely embedded in the kinetic constant." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000013', 'catalyst', 'Substance that accelerates the velocity of a chemical reaction without itself being consumed or transformed. This effect is achieved by lowering the free energy of the transition state." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000014', 'enzyme', 'A protein that catalyzes a chemical reaction. The word comes from en (\"at\" or \"in\") and simo (\"leaven\" or \"yeast\")." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000015', 'substrate', 'Molecule which is acted upon by an enzyme. The substrate binds with the enzymes active site, and the enzyme catalyzes a chemical reaction involving the substrate." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000016', 'unimolecular rate constant', 'Numerical parameter that quantifies the velocity of a chemical reaction involving only one reactant.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000017', 'bimolecular rate constant', 'Numerical parameter that quantifies the velocity of a chemical reaction involving two reactants." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000018', 'trimolecular rate constant', 'Numerical parameter that quantifies the velocity of a chemical reaction involving three reactants.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000019', 'modifier', 'Substance that changes the velocity of a process without\nitself being consumed or transformed by the reaction." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000020', 'inhibitor', 'Substance that decreases the probability of a chemical reaction without itself being consumed or transformed by the reaction." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000021', 'potentiator', 'Substance that increases the probability of a chemical reaction without\nitself being consumed or transformed by the reaction. This effect is achieved by increasing the difference of free energy between the reactant(s) and the product(s)" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000022', 'forward unimolecular rate constant', 'Numerical parameter that quantifies the forward velocity of a chemical\nreaction involving only one reactant. This parameter encompasses all the contributions to the velocity except the quantity of the reactant." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000023', 'forward bimolecular rate constant', 'Numerical parameter that quantifies the forward velocity of a chemical reaction involving two reactants. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000024', 'forward trimolecular rate constant', 'Numerical parameter that quantifies the forward velocity of a chemical\nreaction involving three reactants. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000025', 'catalytic rate constant', 'Numerical parameter that quantifies the velocity of an enzymatic reaction." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000026', 'new term name', 'none" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000027', 'Michaelis constant', 'Substrate concentration at which the velocity of reaction is half its maximum. Michaelis constant is an experimental parameter. According to the underlying molecular mechanism it can be interpreted differently in terms of microscopic constants." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000028', 'enzymatic rate law for irreversible non-modulated non-interacting unireactant enzymes', 'Kinetics of enzymes that react only with one substance, their substrate. The enzymes do not catalyse the reactions in both directions." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000029', 'Henri-Michaelis-Menten rate law', 'First general rate equation for reactions involving enzymes, it was presented in \"Victor Henri. Lois Générales de lAction des Diastases. Paris, Hermann, 1903.\". The reaction is assumed to be made of a reversible of the binding of the substrate to the enzyme, followed by the breakdown of the complex generating the product. Ten years after Henri, Michaelis and Menten presented a variant of his equation, based on the hypothesis that the dissociation rate of the substrate was much larger than the rate of the product generation. Leonor Michaelis, Maud Menten (1913). Die Kinetik der Invertinwirkung, Biochem. Z. 49:333-369." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000030', 'Van Slyke-Cullen rate law', 'Rate-law presented in \"Donald D. Van Slyke and Glenn E. Cullen. The mode of action of urease and of enzymes in general. J. Biol. Chem., Oct 1914; 19: 141-180\". It assumes that the enzymatic reaction occurs as two irreversible steps.E+S -> ES -> E+P. Although of the same form than the Henri-Michaelis-Menten equation, it is semantically different since K now represents the ratio between the production rate and the association rate of the enzyme and the substrate." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000031', 'Briggs-Haldane rate law', 'The Briggs-Haldane rate law is a general rate equation that does not require the restriction of equilibrium of Henri-Michaelis-Menten or irreversible reactions of Van Slyke, but instead make the hypothesis that the complex enzyme-substrate is in quasi-steady-state. Although of the same form than the Henri-Michaelis-Menten equation, it is semantically different since Km now represents a pseudo-equilibrium constant, and is equal to the ratio between the rate of consumption of the complex (sum of dissociation of substrate and generation of product) and the association rate of the enzyme and the substrate." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000032', 'reverse unimolecular rate constant', 'Numerical parameter that quantifies the reverse velocity of a chemical reaction involving only one product. This parameter encompasses all the contributions to the velocity except the quantity of the product." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000033', 'reverse bimolecular rate constant', 'Numerical parameter that quantifies the reverse velocity of a chemical reaction involving only one product. This parameter encompasses all the contributions to the velocity except the quantity of the product." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000034', 'reverse trimolecular rate constant', 'Numerical parameter that quantifies the reverse velocity of a chemical reaction involving three products. This parameter encompasses all the contributions to the velocity except the quantity of the products." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000035', 'forward unimolecular rate constant, continuous case', 'Numerical parameter that quantifies the forward velocity of a chemical reaction involving only one reactant. This parameter encompasses all the contributions to the velocity except the quantity of the reactant. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000036', 'forward bimolecular rate constant, continuous case', 'Numerical parameter that quantifies the forward velocity of a chemical reaction involving two reactants. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000037', 'forward trimolecular rate constant, continuous case', 'Numerical parameter that quantifies the forward velocity of a chemical reaction involving three reactants. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000038', 'reverse unimolecular rate constant, continuous case', 'Numerical parameter that quantifies the reverse velocity of a chemical reaction involving only one product. This parameter encompasses all the contributions to the velocity except the quantity of the product. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000039', 'reverse bimolecular rate constant, continuous case', 'Numerical parameter that quantifies the reverse velocity of a chemical reaction involving only one product. This parameter encompasses all the contributions to the velocity except the quantity of the product. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000040', 'reverse trimolecular rate constant, continuous case', 'Numerical parameter that quantifies the reverse velocity of a chemical reaction involving three products. This parameter encompasses all the contributions to the velocity except the quantity of the products. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000041', 'mass action rate law for irreversible reactions', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000042', 'mass action rate law for reversible reactions', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000043', 'mass action rate law for zeroth order irreversible reactions', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is constant." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000044', 'mass action rate law for first order irreversible reactions', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of one reactant." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000045', 'mass action rate law for second order irreversible reactions', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to two reactant quantity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000046', 'zeroth order rate constant', 'Numerical parameter that quantifies the velocity of a chemical reaction independant of the reactant quantities. This parameter encompasses all the contributions to the velocity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000047', 'mass action rate law for zeroth order irreversible reactions, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is constant. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000048', 'forward zeroth order rate constant, continuous case', 'Numerical parameter that quantifies the forward velocity of a chemical reaction independant of the reactant quantities. This parameter encompasses all the contributions to the velocity. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000049', 'mass action rate law for first order irreversible reactions, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of one reactant. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000050', 'mass action rate law for second order irreversible reactions, one reactant', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products, and the change of a product quantity is proportional to the square of one reactant quantity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000051', 'new term name', '" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000052', 'mass action rate law for second order irreversible reactions, one reactant, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the square of one reactant quantity. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000053', 'mass action rate law for second order irreversible reactions, two reactants', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of two reactants. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000054', 'mass action rate law for second order irreversible reactions, two reactants, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the product of two reactant quantities. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000055', 'mass action rate law for third order irreversible reactions', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to three reactant quantities." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000056', 'mass action rate law for third order irreversible reactions, one reactant', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the cube of one reactant quantity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000057', 'mass action rate law for third order irreversible reactions, one reactant, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products, and the change of a product quantity is proportional to the cube of one reactant quantity. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000058', 'mass action rate law for third order irreversible reactions, two reactants', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of one reactant and the square of the quantity of the other reactant." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000059', 'mass action rate law for third order irreversible reactions, two reactants, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of one reactant and the square of the quantity of the other reactant. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000060', 'mass action rate law for third order irreversible reactions, three reactants', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of three reactants." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000061', 'mass action rate law for third order irreversible reactions, three reactants, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products, and the change of a product quantity is proportional to the product of three reactant quantities. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000062', 'continuous framework', 'Modelling approach where the quantities of participants are considered continuous, and represented by real values. The associated simulation methods make use of differential equations." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000063', 'discrete framework', 'Modelling approach where the quantities of participants are considered discrete, and represented by integer values. The associated simulation methods can be deterministic or stochastic. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000064', 'mathematical expression', 'Formal representation of a calculus linking parameters and variables of a model." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000065', 'forward zeroth order rate constant, discrete case', 'Numerical parameter that quantifies the forward velocity of a chemical reaction independant of the reactant quantities. This parameter encompasses all the contributions to the velocity. It is to be used in a reaction modelled using a discrete framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000066', 'forward unimolecular rate constant, discrete case', 'Numerical parameter that quantifies the forward velocity of a chemical reaction involving only one reactant. This parameter encompasses all the contributions to the velocity except the quantity of the reactant. It is to be used in a reaction modelled using a discrete framework. \n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000067', 'forward bimolecular rate constant, discrete case', 'Numerical parameter that quantifies the forward velocity of a chemical reaction involving two reactants. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. It is to be used in a reaction modelled using a discrete framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000068', 'forward trimolecular rate constant, discrete case', 'Numerical parameter that quantifies the forward velocity of a chemical reaction involving three reactants. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. It is to be used in a reaction modelled using a discrete framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000069', 'mass action rate law for zeroth order reversible reactions', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000070', 'mass action rate law for zeroth order forward, first order reverse, reversible reactions, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant. The rate of the reverse process is proportional to the quantity of one product. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000071', 'mass action rate law for zeroth order forward, second order reverse, reversible reactions, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant. The rate of the reverse process is proportional totwo product quantities." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000072', 'mass action rate law for zeroth order forward, second order reverse, reversible reactions, one product, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant. The rate of the reverse process is proportional to the square of one product quantity. It is to be used in a reaction modelled using a continuous framework.\n\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000073', 'mass action rate law for zeroth order forward, second order reverse, reversible reactions, two products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant. The rate of the reverse process is proportional to the product of two product quantities. It is to be used in a reaction modelled using a continuous framework.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000074', 'mass action rate law for zeroth order forward, third order reverse, reversible reactions, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant. The rate of the reverse process is proportional to three product quantities." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000075', 'mass action rate law for zeroth order forward, third order reverse, reversible reactions, one product, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant. The rate of the reverse process is proportional to the cube of one product quantity. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000076', 'mass action rate law for zeroth order forward, third order reverse, reversible reactions, two products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant. The rate of the reverse process is proportional to the quantity of one product and the square of the quantity of the other product. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000077', 'mass action rate law for zeroth order forward, third order reverse, reversible reactions, three products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is constant. The rate of the reverse process is proportional to the product of three product quantities. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000078', 'mass action rate law for first order reversible reactions', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000079', 'mass action rate law for first order forward, zeroth order reverse, reversible reactions, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is constant. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000080', 'mass action rate law for first order forward, first order reverse, reversible reactions, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is proportional to the quantity of one product. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000081', 'mass action rate law for first order forward, second order reverse, reversible reactions', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is proportional to two product quantities." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000082', 'mass action rate law for first order forward, second order reverse, reversible reactions, one product, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is proportional to the square of one product quantity. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000083', 'mass action rate law for first order forward, second order reverse, reversible reactions, two products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is proportional to the product of two product quantities. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000084', 'mass action rate law for first order forward, third order reverse, reversible reactions', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is proportional to three product quantities." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000085', 'mass action rate law for first order forward, third order reverse, reversible reactions, one product, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is proportional to the cube of one product quantity. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000086', 'mass action rate law for first order forward, third order reverse, reversible reactions, two products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is proportional to the quantity of one product and the square of the quantity of the other product. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000087', 'mass action rate law for first order forward, third order reverse, reversible reactions, three products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant. The rate of the reverse process is proportional to the product of three product quantities. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000088', 'mass action rate law for second order reversible reactions', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to two reactant quantities." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000089', 'mass action rate law for second order forward, reversible reactions, one reactant', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000090', 'mass action rate law for second order forward, zeroth order reverse, reversible reactions, one reactant, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is constant. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000091', 'mass action rate law for second order forward, first order reverse, reversible reactions, one reactant, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is proportional to the quantity of one product. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000092', 'mass action rate law for second order forward, second order reverse, reversible reactions, one reactant', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is proportional to the quantity of two products." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000093', 'mass action rate law for second order forward, second order reverse, reversible reactions, one reactant, one product, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is proportional to the square of one product quantity. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000094', 'mass action rate law for second order forward, second order reverse, reversible reactions, two products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is proportional to the product of two product quantities. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000095', 'mass action rate law for second order forward, third order reverse, reversible reactions, one reactant', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is proportional to the quantity of three products." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000096', 'mass action rate law for second order forward, third order reverse, reversible reactions, one reactant, one product, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is proportional to the cube of one product quantity. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000097', 'mass action rate law for second order forward, third order reverse, reversible reactions, one reactant, two products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is proportional to the quantity of one product and the square of the quantity of the other product. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000098', 'mass action rate law for second order forward, third order reverse, reversible reactions, one reactant, three products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the square of one reactant quantity. The rate of the reverse process is proportional to the product of three product quantities. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000099', 'mass action rate law for second order forward, reversible reactions, two reactants', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000100', 'mass action rate law for second order forward, zeroth order reverse, reversible reactions, two reactants, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is constant. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000101', 'mass action rate law for second order forward, first order reverse, reversible reactions, two reactants, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the quantity of one product. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000102', 'mass action rate law for second order forward, second order reverse, reversible reactions, two reactants', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the quantity of two products." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000103', 'mass action rate law for second order forward, second order reverse, reversible reactions, two reactants, one product, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the square of one product quantity. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000104', 'mass action rate law for second order forward, second order reverse, reversible reactions, two reactants, two products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the product of two product quantities. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000105', 'mass action rate law for second order forward, third order reverse, reversible reactions, two reactants', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the quantity of three products." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000106', 'mass action rate law for second order forward, third order reverse, reversible reactions, two reactants, one product, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the cube of one product quantity. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000107', 'mass action rate law for second order forward, third order reverse, reversible reactions, two reactants, two products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the quantity of one product and the square of the quantity of the other product. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000108', 'mass action rate law for second order forward, third order reverse, reversible reactions, two reactants, three products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of two reactant quantities. The rate of the reverse process is proportional to the product of three product quantities. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000109', 'mass action rate law for third order reversible reactions', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of a reactant quantity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000110', 'mass action rate law for third order forward, reversible reactions, two reactants', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000111', 'mass action rate law for third order forward, zeroth order reverse, reversible reactions, two reactants, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is constant. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000112', 'mass action rate law for third order forward, first order reverse, reversible reactions, two reactants, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the quantity of one product. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000113', 'mass action rate law for third order forward, second order reverse, reversible reactions, two reactants', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the quantity of two products." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000114', 'mass action rate law for third order forward, second order reverse, reversible reactions, two reactants, one product, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the square of one product quantity. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000115', 'mass action rate law for third order forward, second order reverse, reversible reactions, two reactants, two products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the product of two product quantities. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000116', 'mass action rate law for third order forward, third order reverse, reversible reactions, two reactants', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the quantity of three products." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000117', 'mass action rate law for third order forward, third order reverse, reversible reactions, two reactants, one product, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the cube of one product quantity. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000118', 'mass action rate law for third order forward, third order reverse, reversible reactions, two reactants, two products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the quantity of one product and the square of the quantity of the other product. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000119', 'mass action rate law for third order forward, third order reverse, reversible reactions, two reactants, three products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the quantity of one reactant and the square of quantity of the other reactant. The rate of the reverse process is proportional to the product of three product quantities. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000120', 'mass action rate law for third order forward, reversible reactions, three reactants', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000121', 'mass action rate law for third order forward, zeroth order reverse, reversible reactions, three reactants, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is constant. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000122', 'mass action rate law for third order forward, first order reverse, reversible reactions, three reactants, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the quantity of one product. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000123', 'mass action rate law for third order forward, second order reverse, reversible reactions, three reactants', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the quantity of two products." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000124', 'mass action rate law for third order forward, second order reverse, reversible reactions, three reactants, one product, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the square of one product quantity. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000125', 'mass action rate law for third order forward, second order reverse, reversible reactions, three reactants, two products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the product of two product quantities. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000126', 'mass action rate law for third order forward, third order reverse, reversible reactions, three reactants', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the quantity of three products." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000127', 'mass action rate law for third order forward, third order reverse, reversible reactions, three reactants, one product, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the cube of one product quantity. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000128', 'mass action rate law for third order forward, third order reverse, reversible reactions, three reactants, two products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the quantity of one product and the square of the quantity of the other product. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000129', 'mass action rate law for third order forward, third order reverse, reversible reactions, three reactants, three products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the product of three reactant quantities. The rate of the reverse process is proportional to the product of three product quantities. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000130', 'mass action rate law for third order forward, reversible reactions, one reactant', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000131', 'mass action rate law for third order forward, zeroth order reverse, reversible reactions, one reactant, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is constant. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000132', 'mass action rate law for third order forward, first order reverse, reversible reactions, one reactant, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the quantity of one product. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000133', 'mass action rate law for third order forward, second order reverse, reversible reactions, one reactant', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the quantity of two products." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000134', 'mass action rate law for third order forward, second order reverse, reversible reactions, one reactant, one product, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the square of one product quantity. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000135', 'mass action rate law for third order forward, second order reverse, reversible reactions, one reactant, two products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the product of two product quantities. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000136', 'mass action rate law for third order forward, third order reverse, reversible reactions, one reactant', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the quantity of three products." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000137', 'mass action rate law for third order forward, third order reverse, reversible reactions, one reactant, one product, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the cube of one product quantity. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000138', 'mass action rate law for third order forward, third order reverse, reversible reactions, one reactant, two products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the quantity of one product and the square of the quantity of the other product. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000139', 'mass action rate law for third order forward, third order reverse, reversible reactions, one reactant, three products, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does include a reverse process that creates the reactants from the products. The rate of the forward process is proportional to the cube of one reactant quantity. The rate of the reverse process is proportional to the product of three product quantities. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000140', 'mass action rate law for zeroth order irreversible reactions, discrete scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is constant. It is to be used in a reaction modelled using a discrete framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000141', 'mass action rate law for first order irreversible reactions, discrete scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of one reactant. It is to be used in a reaction modelled using a discrete framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000142', 'mass action rate law for second order irreversible reactions, one reactant, discrete scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the square of one reactant quantity. It is to be used in a reaction modelled using a discrete framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000143', 'mass action rate law for second order irreversible reactions, two reactants, discrete scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of two reactants. It is to be used in a reaction modelled using a discrete framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000144', 'mass action rate law for third order irreversible reactions, one reactant, discrete scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the cube of one reactant quantity. It is to be used in a reaction modelled using a discrete framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000145', 'mass action rate law for third order irreversible reactions, two reactants, discrete scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of one reactant and the square of the quantity of the other reactant. It is to be used in a reaction modelled using a discrete framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000146', 'mass action rate law for third order irreversible reactions, three reactants, discrete scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of three reactants. It is to be used in a reaction modelled using a discrete framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000147', 'thermodynamic temperature', 'Temperature is the physical property of a system which underlies the common notions of \"hot\" and \"cold\"; the material with the higher temperature is said to be hotter. Temperature is a quantity related to the average kinetic energy of the particles in a substance. The 10th Conference Generale des Poids et Mesures decided to define the thermodynamic temperature scale by choosing the triple point of water as the fundamental fixed point, and assigning to it the temperature 273,16 degrees Kelvin, exactly (0.01 degree Celsius)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000148', 'temperature difference', 'Quantity resulting from the difference between two thermodynamic temperatures. A difference or interval of temperature may be expressed in Kelvins or in degrees Celsius.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000149', 'number of substrates', 'Number of molecules which are acted upon by an enzyme." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000150', 'enzymatic rate law for irreversible non-modulated non-interacting reactant enzymes', 'Kinetics of enzymes that react with one or several substances, their substrates, that bind independently. The enzymes do not catalyse the reactions in both directions. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000151', 'enzymatic rate law for irreversible non-modulated non-interacting bireactant enzymes', 'Kinetics of enzymes that react with two substances, their substrates, that bind independently. The enzymes do not catalyse the reactions in both directions. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000152', 'enzymatic rate law for irreversible non-modulated non-interacting trireactant enzymes', 'Kinetics of enzymes that react with three substances, their substrates, that bind independently. The enzymes do not catalyse the reactions in both directions." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000153', 'forward rate constant', 'Numerical parameter that quantifies the forward velocity of a chemical reaction. This parameter encompasses all the contributions to the velocity except the quantity of the reactants." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000154', 'forward rate constant, continuous case', 'Numerical parameter that quantifies the forward velocity of a chemical reaction. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000155', 'forward rate constant, discrete case', 'Numerical parameter that quantifies the forward velocity of a chemical reaction. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. It is to be used in a reaction modelled using a discrete framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000156', 'reverse rate constant', 'Numerical parameter that quantifies the forward velocity of a chemical reaction. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000157', 'number of reactants', 'Number of different substances consumed by a chemical reaction." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000158', 'order of a reaction with respect to a reactant', 'The order of a reaction with respect to a certain reactant is defined as the power to which its concentration term in the rate equation is raised." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000159', 'non-integral order rate constant', 'Numerical parameter that quantifies the velocity of a chemical reaction where reactants have non-integral orders. This parameter encompasses all the contributions to the velocity except the quantity of the reactants." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000160', 'forward non-integral order rate constant', 'Numerical parameter that quantifies the forward velocity of a chemical reaction where reactants have non-integral orders. This parameter encompasses all the contributions to the velocity except the quantity of the reactants." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000161', 'reverse non-integral order rate constant', 'Numerical parameter that quantifies the reverse velocity of a chemical reaction where products have non-integral orders. This parameter encompasses all the contributions to the velocity except the quantity of the products." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000162', 'forward zeroth order rate constant', 'Numerical parameter that quantifies the forward velocity of a chemical reaction independant of the reactant quantities. This parameter encompasses all the contributions to the velocity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000163', 'mass action rate law for irreversible reactions, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000164', 'second order irreversible mass action kinetics, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to two reactant quantity. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000165', 'third order irreversible mass action kinetics, continuous scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to three reactant quantities. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000166', 'mass action rate law for irreversible reactions, discrete scheme', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme does not include any reverse process that creates the reactants from the products. It is to be used in a reaction modelled using a discrete framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000167', 'biochemical or transport reaction', 'An event involving one or more physical entities that modifies the structure, location or free energy of at least one of the participants." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000168', 'control', 'Modification of the execution of an event or a process." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000169', 'inhibition', 'Negative modulation of the execution of a process." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000170', 'stimulation', 'Positive modulation of the execution of a process." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000171', 'necessary stimulation', 'Control that is necessary to the execution of a process." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000172', 'catalysis', 'Modification of the velocity of a reaction by lowering the energy of the transition state." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000173', 'and', 'All the preceding events or participating entities are necessary to perform the control." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000174', 'or', 'Any of the preceding events or participating entities are necessary to perform the control." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000175', 'xor', 'Only one of the preceding events or participating entities can perform the control at one time." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000176', 'biochemical reaction', 'An event involving one or more chemical entities that modifies the electrochemical structure of at least one of the participants.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000177', 'non-covalent binding', 'Interaction between several biochemical entities that results in the formation of a non-covalent complex" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000178', 'cleavage', 'Rupture of a covalent bond resulting in the conversion of one physical entity into several physical entities." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000179', 'degradation', 'Complete disappearance of a physical entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000180', 'dissociation', 'Transformation of a non-covalent complex that results in the formation of several independent biochemical entities" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000181', 'conformational transition', 'Biochemical reaction that does not result in the modification of covalent bonds of reactants, but rather modifies the conformation of some reactants, that is the relative position of their atoms in space." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000182', 'conversion', 'Biochemical reaction that results in the modification of some covalent bonds." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000183', 'transcription', 'Process through which a DNA sequence is copied to produce a complementary RNA." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000184', 'translation', 'Process in which a polypeptide chain is produced from a messenger RNA." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000185', 'transport reaction', 'Movement of a physical entity without modification of the structure of the entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000186', 'maximal velocity', 'Limiting maximal velocity of an enzymatic reaction, reached when the substrate is in large excess and all the enzyme is complexed." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000187', 'Henri-Michaelis-Menten equation, Vmax form', 'Version of Henri-Michaelis-Menten equation where kp*\[E\]t is replaced by the maximal velocity, Vmax, reached when all the enzyme is active. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000188', 'number of biochemical items', 'A number of objects of the same type, identical or different, involved in a biochemical event." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000189', 'number of binding sites', 'Number of regions on a reactant to which specific other reactants, in this context collectively called ligands, form a chemical bond." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000190', 'Hill coefficient', 'Empirical parameter created by Archibald Vivian Hill to describe the cooperative binding of oxygen on hemoglobine (Hill (1910). The possible effects of the aggregation of the molecules of haemoglobin on its dissociation curves. J Physiol 40: iv-vii)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000191', 'Hill constant', 'Empirical constant created by Archibald Vivian Hill to describe the cooperative binding of oxygen on hemoglobine (Hill (1910). The possible effects of the aggregation of the molecules of haemoglobin on its dissociation curves. J Physiol 40: iv-vii). Different from a microscopic dissociation constant, it has the dimension of concentration to the power of the Hill coefficient." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000192', 'Hill-type rate law, generalised form', 'Empirical equation created by Archibald Vivian Hill to describe the cooperative binding of oxygen on hemoglobine (Hill (1910). The possible effects of the aggregation of the molecules of haemoglobin on its dissociation curves. J Physiol 40: iv-vii)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000193', 'equilibrium or steady-state constant', 'Constant with the dimension of a powered concentration. It is determined at half-saturation, half-activity etc. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000194', 'pseudo-dissociation constant', 'Dissociation constant equivalent to an intrinsic microscopic dissociation constant, but obtained from an averaging process, for instance by extracting the root of a Hill constant. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000195', 'Hill-type rate law, microscopic form', 'Hill equation rewritten by creating a pseudo-microscopic constant, equal to the Hill constant powered to the opposite of the Hill coefficient." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000196', 'concentration of an entity pool', 'The amount of an entity per unit of volume. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000197', 'specific concentration of an entity', 'Concentration of an object divided by the value of another parameter having the dimension of a concentration." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000198', 'Hill-type rate law, reduced form', 'Hill equation rewritten by replacing the concentration of reactant with its reduced form, that is the concentration divide by a pseudo-microscopic constant, equal to the Hill constant powered to the opposite of the Hill coefficient." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000199', 'normalised enzymatic rate law for unireactant enzymes', 'Kinetics of enzymes that react only with one substance, their substrate. The total enzyme concentration is considered to be equal to 1, therefore the maximal velocity equals the catalytic constant." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000200', 'redox reaction', 'Chemical process in which atoms have their oxidation number (oxidation state) changed." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000201', 'oxidation', 'Chemical process during which a molecular entity loses electrons." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000202', 'reduction', 'Chemical process in which a molecular entity gain electrons." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000203', 'duplication', 'Reaction in which a reactant gives birth to two products identical to itself." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000204', 'DNA replication', 'Process in which a DNA duplex is transformed into two identical DNA duplexes." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000205', 'composite biochemical process', 'Process that involves the participation of chemical or biological entities and is composed of several elementary steps or reactions. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000206', 'competitive inhibitor', 'Substance that decreases the probability of a chemical reaction, without itself being consumed or transformed by the reaction, by stericaly hindering the interaction between reactants." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000207', 'non-competitive inhibitor', 'Substance that decreases the probability of a chemical reaction, without itself being consumed or transformed by the reaction, and without sterically hindering the interaction between reactants. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000208', 'acid-base reaction', 'Chemical reaction where a proton is given by a compound, the acid, to another one, the base (Brønsted-Lowry definition). An alternative, more general, definition is a reaction where a compound, the base, gives a pair of electrons to another, the acid (Lewis definition)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000209', 'ionisation', 'Ionization is the physical process of converting an atom or molecule into an ion by changing the difference between the number of protons and electrons. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000210', 'addition of a chemical group', 'Covalent reaction that results in the addition of a chemical group on a molecule." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000211', 'removal of a chemical group', 'Covalent reaction that results in the removal of a chemical group from a molecule." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000212', 'protonation', 'Addition of a proton (H+) to a chemical entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000213', 'deprotonation', 'Removal of a proton (hydrogen ion H+) from a chemical entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000214', 'methylation', 'Addition of a methyl group (-CH3) to a chemical entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000215', 'acetylation', 'Addition of an acetyl group (-COCH3) to a chemical entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000216', 'phosphorylation', 'Addition of a phosphate group (-H2PO4) to a chemical entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000217', 'glycosylation', 'Addition of a saccharide group to a chemical entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000218', 'palmitoylation', 'Addition of a palmitoyl group (CH3-\[CH2\]14-CO-) to a chemical entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000219', 'myristoylation', 'Addition of a myristoyl (CH3-\[CH2\]12-CO-) to a chemical entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000220', 'sulfation', 'Addition of a sulfate group (SO4--) to a chemical entity. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000221', 'prenylation', 'Addition of a prenyl group (generic sense) to a chemical entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000222', 'farnesylation', 'Addition of a farnesyl group (CH2-CH=C(CH3)-CH2-CH2-CH=C(CH3)-CH2-CH2-CH=C(CH3)2) to a chemical entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000223', 'geranylgeranylation', 'Addition of a geranylgeranyl group (CH2-CH=C(CH3)-CH2-CH2-CH=C(CH3)-CH2-CH2-CH=C(CH3)-CH2-CH2-CH=C(CH3)2) to a chemical entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000224', 'ubiquitination', 'Covalent linkage to the protein ubiquitin. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000225', 'delay', 'Time during which some action is awaited." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000226', 'density of an entity pool', 'A quantitative measure of an amount or property of an entity expressed in terms of another dimension, such as unit length, area or volume." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000227', 'mass density of an entity', 'The mass of an entity expressed with reference to another dimension, such as unit length, area or volume." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000228', 'volume density of an entity', 'Mass of an entity per unit volume." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000229', 'area density of an entity', 'The mass of an entity per unit of surface area." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000230', 'linear density of an entity', 'Mass of an entity per unit length." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000231', 'occurring entity representation', 'Representation of an entity that manifests, unfolds or develops through time, such as a discrete event, or a mutual or reciprocal action or influence that happens between participating physical entities, and/or other occurring entities. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000232', 'obsolete event', 'A phenomenon that takes place and which may be observable, or may be determined to have occurred as the result of an action or process." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000233', 'hydroxylation', 'Addition of an hydroxyl group (-OH) to a chemical entity. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000234', 'logical framework', 'Modelling approach, pioneered by Rene Thomas and Stuart Kaufman, where the evolution of a system is described by the transitions between discrete activity states of \"genes\" that control each other." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000235', 'participant', 'Entity that affects or is affected by an event." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000236', 'physical entity representation', 'Representation of an entity that may participate in an interaction, a process or relationship of significance.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000237', 'logical combination', 'Combining the influence of several entities or events in a unique influence." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000238', 'not', 'The preceding event or participating entity cannot participate to the control. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000239', 'allosteric control', 'Regulation of the influence of a reaction participant by binding an effector to a binding site of the participant different of the site of the participant conveying the influence." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000240', 'material entity', 'A real thing that is defined by its physico-chemical structure.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000241', 'functional entity', 'A real thing, defined by its properties or the actions it performs, rather than it physico-chemical structure." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000242', 'channel', 'A component that allows another component to pass through itself, possibly connecting different compartments." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000243', 'gene', 'A locatable region of genomic sequence, corresponding to a unit of inheritance, which is associated with regulatory regions, transcribed regions and/or other functional sequence regions.\n\nSequence Ontology SO:0000704" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000244', 'receptor', 'Participating entity that binds to a specific physical entity and initiates the response to that physical entity.The original concept of the receptor was introduced independently at the end of the 19th century by John Newport Langley (1852-1925) and Paul Ehrlich (1854-1915).\n\nLangley JN.On the reaction of cells and of nerve-endings to certain poisons, chiefly as regards the reaction of striated muscle to nicotine and to curari. J Physiol. 1905 Dec 30;33(4-5):374-413." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000245', 'macromolecule', 'Molecular entity mainly built-up by the repetition of pseudo-identical units.\n\nCHEBI:33839" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000246', 'information macromolecule', 'Macromolecule whose sequence is encoded in the genome of living organisms." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000247', 'simple chemical', 'Simple, non-repetitive chemical entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000248', 'chemical macromolecule', 'Macromolecule whose sequence is not directly encoded in the genome." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000249', 'polysaccharide', 'Macromolecule consisting of a large number of monosaccharide residues linked by glycosidic bonds.\n\nCHEBI:18154" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000250', 'ribonucleic acid', 'Macromolecule formed by a repetition of ribonucleosides linked by phosphodiester bonds.\n\nCHEBI:33697" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000251', 'deoxyribonucleic acid', 'Polymer composed of nucleotides containing deoxyribose and linked by phosphodiester bonds.\n\nCHEBI:16991 " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000252', 'polypeptide chain', 'Naturally occurring macromolecule formed by the repetition of amino-acid residues linked by peptidic bonds. A polypeptide chain is synthesized by the ribosome.\n\nCHEBI:16541" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000253', 'non-covalent complex', 'Entity composed of several independant components that are not linked by covalent bonds." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000254', 'electrical resistance', 'Measure of the degree to which an object opposes the passage of an electric current. The SI unit of electrical resistance is the ohm." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000255', 'physical characteristic', 'Parameter characterising a physical system or the environment, and independent of lifes influence." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000256', 'biochemical parameter', 'Parameter that depends on the biochemical properties of a system." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000257', 'conductance', 'Measure of how easily electricity flows along a certain path through an electrical element. The SI derived unit of conductance is the Siemens." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000258', 'capacitance', 'Measure of the amount of electric charge stored (or separated) for a given electric potential. The unit of capacitance id the Farad." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000259', 'voltage', 'Difference of electrical potential between two points of an electrical network, expressed in volts." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000260', 'enzymatic rate law for simple competitive inhibition of irreversible unireactant enzymes by one inhibitor', 'Inhibition of a unireactant enzyme by one inhibitor that binds once to the free enzyme and prevents the binding of the substrate. The enzymes do not catalyse the reactions in both directions. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000261', 'inhibitory constant', 'Dissociation constant of a compound from a target of which it inhibits the function. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000262', 'enzymatic rate law for simple uncompetitive inhibition of irreversible unireactant enzymes', 'Inhibition of a unireactant enzyme by one inhibitor that binds only to the complex enzyme-substrate and totally prevent the catalysis. The enzymes do not catalyse the reactions in both directions. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000263', 'relative equilibrium constant', 'Ratio of an equilibrium constant in a given condition by the same equilibrium constant is not fullfilled." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000264', 'relative inhibition constant', 'Ratio of the dissociation constant of an inhibitor from the complex enzyme-substrate on the dissociation constant of an inhibitor from the free enzyme." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000265', 'enzymatic rate law for simple mixed-type inhibition of irreversible unireactant enzymes', 'Inhibition of a unireactant enzyme by one inhibitor that can bind to the complex enzyme-substrate and the free enzyme, possibly with different equilibrium constant, and totally prevent the catalysis. The enzymes do not catalyse the reactions in both directions." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000266', 'enzymatic rate law for simple irreversible non-competitive inhibition of unireactant enzymes', 'Inhibition of a unireactant enzyme by one inhibitor that can bind to the complex enzyme-substrate and the free enzyme with the same equilibrium constant, and totally prevent the catalysis." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000267', 'enzymatic rate law for competitive inhibition of irreversible unireactant enzymes by one inhibitor', 'Inhibition of a unireactant enzyme by one inhibitor that can bind one or several times to the free enzyme, and prevent the binding of the substrate. The enzymes do not catalyse the reactions in both directions.\n\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000268', 'enzymatic rate law', 'Enzyme kinetics is the study of the rates of chemical reactions that are catalysed by enzymes, how this rate is controlled, and how drugs and poisons can inhibit its activity. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000269', 'enzymatic rate law for unireactant enzymes', 'Kinetics of enzymes that catalyse the transformation of only one substrate. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000270', 'enzymatic rate law for competitive inhibition of irreversible unireactant enzymes by exclusive inhibitors', 'Inhibition of a unireactant enzyme by inhibitors that bind to the free enzyme on the same binding site than the substrate. The enzymes do not catalyse the reactions in both directions. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000271', 'enzymatic rate law for competitive inhibition of irreversible unireactant enzymes by two exclusive inhibitors', 'Inhibition of a unireactant enzyme by two inhibitors that bind to the free enzyme on the same binding site than the substrate. The enzymes do not catalyse the reactions in both directions. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000272', 'number of inhibitors', 'Number of entities that inhibit a reaction. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000273', 'enzymatic rate law for competitive inhibition of irreversible unireactant enzymes by non-exclusive non-cooperative inhibitors', 'Inhibition of a unireactant enzyme by inhibitors that bind independently to the free enzyme and preclude the binding of the substrate. The enzymes do not catalyse the reactions in both directions." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000274', 'enzymatic rate law for simple competitive inhibition of irreversible unireactant enzymes by two non-exclusive, non-cooperative inhibitors', 'Inhibition of a unireactant enzyme by two inhibitors that can bind independently once to the free enzyme and preclude the binding of the substrate. The enzymes do not catalyse the reactions in both directions." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000275', 'enzymatic rate law for mixed-type inhibition of irreversible enzymes by mutually exclusive inhibitors', 'Inhibition of a unireactant enzyme by inhibitors that can bind to the complex enzyme-substrate and the free enzyme, possibly with different equilibrium constants, and totally prevent the catalysis. The enzymes do not catalyse the reactions in both directions. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000276', 'enzymatic rate law for mixed-type inhibition of irreversible unireactant enzymes by two inhibitors', 'Inhibition of unireactant enzymes by two inhibitors that can bind to the complex enzyme-substrate and the free enzyme, possibly with different equilibrium constant, and totally prevent the catalysis. The enzymes do not catalyse the reactions in both directions. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000277', 'enzymatic rate law for non-competitive inhibition of irreversible unireactant enzymes by two exclusively binding inhibitors', 'Inhibition of unireactant enzymes by two inhibitors that can bind to the complex enzyme-substrate and the free enzyme with the same equilibrium constant and totally prevent the catalysis. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000278', 'messenger RNA', 'A messenger RNA is a ribonucleic acid synthesized during the transcription of a gene, and that carries the information to encode one or several proteins." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000279', 'pressure', 'Pressure (symbol: p) is the force per unit area applied on a surface in a direction perpendicular to that surface. The unit of pressure is the Pascal (Pa), that is equal to 1 Newton per square meter." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000280', 'ligand', 'In biochemistry, a ligand is an effector, a physical entity that binds to a site on a receptors surface by intermolecular forces." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000281', 'equilibrium constant', 'Quantity characterizing a chemical equilibrium in a chemical reaction, which is a useful tool to determine the concentration of various reactants or products in a system where chemical equilibrium occurs." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000282', 'dissociation constant', 'Equilibrium constant that measures the propensity of a larger object to separate (dissociate) reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into its component ions. The dissociation constant is usually denoted Kd and is the inverse of the affinity constant." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000283', 'acid dissociation constant', 'Equilibrium constant that indicates the extent of dissociation of hydrogen ions from an acid. The equilibrium is that of a proton transfer from an acid, HA, to water, H2O. The term for the concentration of water, \[H2O\], is omitted from the general equilibrium constant expression. Ka=(\[H3O+\]*\[A-\])/(HA)" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000284', 'transporter', 'Participating entity that facilitates the movement of another physical entity from a defined subset of the physical environment (for instance a cellular compartment) to another. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000285', 'material entity of unspecified nature', 'Material entity whose nature is unknown or irrelevant." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000286', 'multimer', 'Non-covalent association of identical, or pseudo-identical, entities. By pseudo-identical entities, we mean biochemical elements that differ chemically, although remaining globally identical in structure and/or function. Examples are homologous subunits in an hetero-oligomeric receptor." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000287', 'EC50', 'Concentration of an active compound at which 50% of its maximal effect is observed. The EC50 is not a pure characteristic of the compound but depends on the conditions or the measurement." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000288', 'IC50', 'Also called half maximal inhibitory concentration, it represents the concentration of an inhibitor substance that is required to suppress 50% of an effect. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000289', 'functional compartment', 'Logical or physical subset of the event space that contains pools, that is sets of participants considered identical when it comes to the event they are involved into. A compartment can have any number of dimensions, including 0, and be of any size including null." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000290', 'physical compartment', 'Specific location of space, that can be bounded or not. A physical compartment can have 1, 2 or 3 dimensions." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000291', 'empty set', 'Entity defined by the absence of any actual object. An empty set is often used to represent the source of a creation process or the result of a degradation process. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000292', 'spatial continuous framework', 'Modelling approach where the quantities of participants are considered continuous, and represented by real values. The associated simulation methods make use of differential equations. The models take into account the distribution of the entities and describe the spatial fluxes. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000293', 'non-spatial continuous framework', 'Modelling approach where the quantities of participants are considered continuous, and represented by real values. The associated simulation methods make use of differential equations. The models do not take into account the distribution of the entities and describe only the temporal fluxes. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000294', 'spatial discrete framework', 'Modelling approach where the quantities of participants are considered discrete, and represented by integer values. The associated simulation methods can be deterministic or stochastic. The models take into account the distribution of the entities and describe the spatial fluxes. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000295', 'non-spatial discrete framework', 'Modelling approach where the quantities of participants are considered discrete, and represented by integer values. The associated simulation methods can be deterministic or stochastic.The models do not take into account the distribution of the entities and describe only the temporal fluxes. \n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000296', 'macromolecular complex', 'Non-covalent complex of one or more macromolecules and zero or more simple chemicals." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000297', 'protein complex', 'Macromolecular complex containing one or more polypeptide chains possibly associated with simple chemicals.\n\nCHEBI:36080" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000298', 'synthetic chemical compound', 'Chemical entity that is engineered by a human-designed process ex-vivo rather than a produced by a living entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000299', 'metabolite', 'Substance produced by metabolism or by a metabolic process." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000300', 'total concentration of enzyme', 'Total amount of enzyme catalysing a reaction, divided by the volume of reaction. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000301', 'total catalytic efficiency', 'Constant representing the actual efficiency of an enzyme at a given concentration, taking into account its microscopic catalytic activity and the rates of substrate binding and dissociation.\n\nNB. The symbol Vmax and the names maximum rate and maximum velocity are in widespread use although under normal circumstances there is no finite substrate concentration at which v = V and hence no maximum in the mathematical sense (Eur. J. Biochem. 128:281-291)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000302', 'catalytic efficiency', 'Constant representing the actual efficiency of an enzyme, taking into account its microscopic catalytic activity and the rates of substrate binding and dissociation." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000303', 'biochemical potential', 'Derivative of a biochemical energy per a substance." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000304', 'pH', 'Negative logarithm (base 10) of the activity of hydrogen in a solution. Ina diluted solution, this activity is equal to the concentration of protons (in fact of ions H3O+). The pH is proportional to the chemical potential of hydrogen, by the relation: pH = -µH ÷ 2.3RT. (with µH=-RTln\[H+\])." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000305', 'pOH', 'Negative logarithm (base 10) of the activity of hydroxyde in a solution. In a diluted solution, this activity is equal to the concentration of ions HO-." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000306', 'pK', 'negative logarithm (base 10) of a dissociation constant." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000307', 'pKa', 'negative logarithm (base 10) of an acid dissociation constant." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000308', 'equilibrium or steady-state characteristic', 'Quantitative parameter that characterises a biochemical equilibrium. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000309', 'dissociation characteristic', 'Quantitative parameter that characterises a dissociation. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000310', 'acid dissociation characteristic', 'Quantitative parameter that characterises an acid-base reaction." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000311', 'heterogeneous nuclear RNA', 'Incompletely processed single strand of messenger ribonucleic acid (mRNA), synthesized from a DNA template in the nucleus of a cell by transcription and containing copies of the introns and exons of a gene." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000312', 'mature messenger RNA', 'Completely processed single strand of messenger ribonucleic acid (mRNA), synthesized from a DNA template in the nucleus of a cell by transcription and containing copies of only the exons of a gene." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000313', 'transfer RNA', 'Small RNA chain (73-93 nucleotides) that transfers a specific amino acid to a growing polypeptide chain at the ribosomal site of protein synthesis during translation. It has a site for amino acid attachment and a three-base region called the anticodon that recognizes the corresponding three-base codon region on mRNA via complementary base pairing. Each type of tRNA molecule can be attached to only one type of amino acid, but because the genetic code is degenerate - that is, it contains multiple codons that specify the same amino acid - multiple types of tRNA molecules bearing different anticodons may carry the same amino acid." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000314', 'ribosomal RNA', 'Type of RNA that is the central component of the ribosome, the protein manufacturing machinery of all living cells." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000315', 'ribozyme', 'RNA molecule that catalyzes a chemical reaction." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000316', 'microRNA', 'Single-stranded RNA molecules thought to regulate the expression of other genes. miRNAs are encoded by genes that are transcribed from DNA but not translated into protein (non-coding RNA)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000317', 'small interfering RNA', 'siRNA are 20-25 nucleotide-long double-stranded RNA molecules involved in the regulation of the expression of specific genes, antiviral mechanisms, shaping the chromatin structure of a genome etc. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000318', 'small nuclear RNA', 'Small RNA molecules that are found within the nucleus of eukaryotic cells. They are involved in a variety of important processes such as RNA splicing (removal of introns from heterogeneous nuclear RNA), regulation of transcription factors or RNA polymerase II and maintaining the telomeres. They are always associated with specific proteins, and the complexes are referred to as small nuclear ribonucleoproteins (snRNP)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000319', 'small nucleolar RNA', 'Small RNA molecules that guide chemical modifications (methylation or pseudouridylation) of ribosomal RNAs (rRNAs) and other RNA genes. They are frequently encoded in the introns of ribosomal proteins and are synthesized by RNA polymerase II, but can also be transcribed as independent (sometimes polycistronic) transcriptional units. snoRNAs are a component in the small nucleolar ribonucleoprotein (snoRNP), which contains snoRNA and proteins. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000320', 'product catalytic rate constant', 'Numerical parameter that quantifies the velocity of product creation by a reversible enzymatic reaction. \n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000321', 'substrate catalytic rate constant', 'Numerical parameter that quantifies the velocity of substrate creation by a reversible enzymatic reaction. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000322', 'Michaelis constant for substrate', 'Substrate concentration at which the velocity of product production by the forward activity of a reversible enzyme is half its maximum. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000323', 'Michaelis constant for product', 'Product concentration at which the velocity of substrate production by the reverse activity of a reversible enzyme is half its maximum. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000324', 'forward maximal velocity', 'Limiting maximal velocity of the forward reaction of a reversible enzyme, reached when the substrate is in large excess and all the enzyme is complexed." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000325', 'reverse maximal velocity', 'Limiting maximal velocity of the reverse reaction of a reversible enzyme, reached when the product is in large excess and all the enzyme is complexed." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000326', 'enzymatic rate law for non-modulated unireactant enzymes', 'Kinetics of enzymes that react only with one substance, their substrate, and are not modulated by other compounds." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000327', 'non-macromolecular ion', 'Chemical entity having a net electric charge." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000328', 'non-macromolecular radical', 'chemical entity possessing an unpaired electron." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000329', 'transcription start site', 'First nucleotide of a gene that is copied in the transcribed RNA.\n\nSequence Ontology SO:0000315" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000330', 'dephosphorylation', 'Removal of a phosphate group (-H2PO4) from a chemical entity. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000331', 'half-life', 'Time interval over which a quantified entity is reduced to half its original value." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000332', 'half-life of an exponential decay', 'Time taken by a quantity decreasing according to a mono-exponential decay to be divided by two. Sometimes called t1/2." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000333', 'monoexponential decay rate law', 'Monotonic decrease of a quantity proportionally to its value." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000334', 'non-coding RNA', 'RNA molecule that is not translated into a protein. \n\nSequence Ontology SO:0000655" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000335', 'gene coding region', 'Portion of DNA or RNA that is transcribed into another RNA, such as a messenger RNA or a non-coding RNA (for instance a transfert RNA or a ribosomal RNA)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000336', 'interactor', 'Entity participating in a physical or functional interaction." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000337', 'association constant', 'Equilibrium constant that measures the propensity of two objects to assemble (associate) reversibly into a larger component. The association constant is usually denoted Ka and is the inverse of the dissociation constant. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000338', 'dissociation rate constant', 'Rate with which a complex dissociates into its components." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000339', 'bimolecular association rate constant', 'Rate with which two components associate into a complex." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000340', 'trimolecular association rate constant', 'Rate with which three components associate into a complex." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000341', 'association rate constant', 'Rate with which components associate into a complex." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000342', 'molecular or genetic interaction', 'Mutual or reciprocal action or influence between molecular entities." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000343', 'genetic interaction', 'A phenomenon whereby an observed phenotype, qualitative or quantative, is not explainable by the simple additive effects of the individual gene pertubations alone. Genetic interaction between perturbed genes is usually expected to generate a defective phenotype. The level of defectiveness is often used to sub-classify this phenomenon.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000344', 'molecular interaction', 'Relationship between molecular entities, based on contacts, direct or indirect. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000345', 'time', 'Fundmental quantity of the measuring system used to sequence events, to compare the durations of events and the intervals between them, and to quantify the motions or the transformation of entities. The SI base unit for time is the SI second. The second is the duration of\n9,192,631,770 periods of the radiation corresponding to the transition\nbetween the two hyperfine levels of the ground state of the caesium 133\natom." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000346', 'temporal measure', 'Fundamental quantity of the measuring system used to sequence events, to compare the durations of events and the intervals between them, and to quantify the motions or the transformation of entities. The SI base unit for time is the SI second. The second is the duration of 9,192,631,770 periods of the radiation corresponding to the transition between the two hyperfine levels of the ground state of the caesium 133 atom." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000347', 'duration', 'Amount of time during which an event persists." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000348', 'exponential time constant', 'Time that it takes for an exponential decay to reach 1/e (about 37%) of the original value. This characterises the frequency response of a first-order, linear time-invariant system. This is also the average lifetime of an element in the decaying set. It is the inverse of the exponential decay constant. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000349', 'inactivation rate constant', 'Kinetic constant describing the rate of an irreversible enzyme inactivation\nby decay of the active enzyme into its inactive form." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000350', 'forward reaction velocity', 'The speed of an enzymatic reaction at a defined concentration of substrate(s) and enzyme." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000352', 'reverse zeroth order rate constant', 'Numerical parameter that quantifies the reverse velocity of a chemical reaction independant of the reactant quantities. This parameter encompasses all the contributions to the velocity. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000353', 'reverse reaction velocity', 'The speed of an enzymatic reaction at a defined concentration of substrate(s) and enzyme. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000354', 'informational molecule segment', 'Fragment of a macromolecule that carries genetic information." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000355', 'conservation law', 'Mathematical expression stating that a quantity is conserved in a system, whatever happens within the boundaries of that system. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000356', 'decay constant', 'Kinetic constant characterising a mono-exponential decay. It is the inverse of the mean lifetime of the continuant being decayed. Its unit is \"per time\". " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000357', 'biological effect of a perturbation', 'Biochemical networks can be affected by external influences. Those influences can be well-defined physical perturbations, such as a light pulse, or a change in temperature but also more complex of not well defined phenomena, for instance a biological process, an experimental setup, or a mutation." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000358', 'phenotype', 'A biochemical network can generate phenotypes or affects biological processes. Such processes can take place at different levels and are independent of the biochemical network itself.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000359', 'mass conservation law', 'A chemical moiety that exists under different forms but is not created nor destroyed in a biochemical system. In any given system such a conserved moiety is characterized by a finite number of particles that exist in the system and is invariant.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000360', 'quantity of an entity pool', 'The enumeration of co-localised, identical biochemical entities of a specific state, which constitute a pool. The form of enumeration may be purely numerical, or may be given in relation to another dimension such as length or volume." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000361', 'amount of an entity pool', 'A numerical measure of the quantity, or of some property, of the entities that constitute the entity pool. \n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000362', 'concentration conservation law', 'If all forms of a moiety exist in a single compartment and the size of that compartment is fixed then the Mass Conservation is also a Concentration Conservation.\n\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000363', 'activation constant', 'Dissociation constant of a potentiator (activator) from a target (e.g. an\nenzyme) of which it activates the function." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000364', 'multimer cardinality', 'Number of monomers composing a multimeric entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000365', 'forward non-integral order rate constant, continuous case', 'Numerical parameter that quantifies the forward velocity of a chemical reaction where reactants have non-integral orders. This parameter encompasses all the contributions to the velocity except the quantity of the reactants.It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000366', 'forward non-integral order rate constant, discrete case', 'Numerical parameter that quantifies the forward velocity of a chemical reaction where reactants have non-integral orders. This parameter encompasses all the contributions to the velocity except the quantity of the reactants. It is to be used in a reaction modelled using a discrete framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000367', 'reverse non-integral order rate constant, discrete case', 'Numerical parameter that quantifies the reverse velocity of a chemical reaction where products have non-integral orders. This parameter encompasses all the contributions to the velocity except the quantity of the products. It is to be used in a reaction modelled using a discrete framework.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000368', 'reverse non-integral order rate constant, continuous case', 'Numerical parameter that quantifies the reverse velocity of a chemical reaction where products have non-integral orders. This parameter encompasses all the contributions to the velocity except the quantity of the products. It is to be used in a reaction modelled using a continuous framework. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000369', 'gene regulatory region', 'Region of a gene that is involved in the modulation of the expression of the gene. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000370', 'Michaelis constant in non-equilibrium situation', 'Michaelis constant derived or experimentally measured under non-equilibrium conditions." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000371', 'Michaelis constant in quasi-steady state situation', 'Michaelis constant derived using a steady-state assumption for enzyme-substrate and enzyme-product intermediates. For example see Briggs-Haldane equation (SBO:0000031)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000372', 'Michaelis constant in irreversible situation', 'Michaelis constant derived assuming enzyme-substrate and enzyme-product intermediates are formed in consecutive irreversible reactions. The constant K is the ratio of the forward rate constants. For example see Van Slyke-Cullen equation (SBO:0000030)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000373', 'Michaelis constant in fast equilibrium situation', 'Michaelis constant as determined in a reaction where the formation of the enzyme-substrate complex occurs at a much faster rate than subsequent steps, and so are assumed to be in a quasi-equilibrium situation. K is equivalent to an equilibrium constant. For example see Henri-Michaelis-Menten equation (SBO:0000029)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000374', 'relationship', 'connectedness between entities and/or interactions representing their relatedness or influence." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000375', 'process', 'A sequential series of actions, motions, or occurrences, such as chemical reactions, that affect one or more entities in a phenomenologically characteristic manner." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000376', 'hydrolysis', 'Decomposition of a compound by reaction with water, where the hydroxyl and H groups are incorporated into different products" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000377', 'isomerisation', 'A reaction in which the principal reactant and principal product are isomers of each other" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000378', 'enzymatic rate law for inhibition of irreversible unireactant enzymes by competing substrates', 'Inhibition of a unireactant enzyme by competing substrates (Sa) that bind to the free enzyme on the same binding site. The enzyme does not catalyse the reactions in both directions.\n\n\n\n\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000379', 'enzymatic rate law for simple competitive inhibition of irreversible unireactant enzymes by two non-exclusive inhibitors', 'Inhibition of a unireactant enzyme by two inhibitors that can bind once to the free enzyme and preclude the binding of the substrate. Binding of one inhibitor may affect binding of the other, or not. The enzymes do not catalyse the reactions in both directions." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000380', 'biochemical coefficient', 'number used as a multiplicative or exponential factor for quantities, expressions or functions" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000381', 'biochemical proportionality coefficient', 'A multiplicative factor for quantities, expressions or functions " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000382', 'biochemical exponential coefficient', 'number used as an exponential factor for quantities, expressions or functions " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000383', 'biochemical cooperative inhibition coefficient', 'The coefficient used to quantify the effect on inhibition constants of multiple inhibitors binding non-exclusively to the enzyme." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000384', 'biochemical inhibitory proportionality coefficient', 'Coefficient that quantifies the effect on inhibition constants of either binding of multiple substrates or inhibitors." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000385', 'biochemical cooperative inhibitor substrate coefficient', 'The coefficient that describes the proportional change of Ks or Ki when inhibitor or substrate is bound, respectively, to the enzyme." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000386', 'enzymatic rate law for inhibition of irreversible unireactant enzymes by single competing substrate', 'Inhibition of a unireactant enzyme by a competing substrate (Sa) that binds to the free enzyme on the same binding site. The enzyme does not catalyse the reactions in both directions." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000387', 'enzymatic rate law for competitive inhibition of irreversible unireactant enzyme by product', 'Inhibition of a unireactant enzyme by a competing product (P) that binds to the free enzyme on the same binding site. The enzyme does not catalyse the reactions in both directions.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000388', 'enzymatic rate law for inhibition of irreversible unireactant enzymes by single competing substrate with product inhibition', 'Inhibition of a unireactant enzyme by a competing substrate (Sa) that binds to the free enzyme on the same binding site, and competitive inhibition by a product (P) and an alternative product (Pa). The enzyme does not catalyse the reactions in both directions.\n " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000389', 'switch value', 'A parameter value taken by a switch, which has a discrete set of values which can be alternated or switched between." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000390', 'boolean switch', 'A parameter that has precisely two discrete values which may be switched between. Usually for the boolean parameter these are indicated as 0 or 1 or True or False." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000391', 'steady state expression', 'A mathematical expression that describes a steady state situation" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000392', 'equivalence', 'Term to signify those material or conceptual entities that are identical in some respect within a frame of reference" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000393', 'production', 'Generation of a material or conceptual entity. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000394', 'consumption', 'Decrease in amount of a material or conceptual entity. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000395', 'encapsulating process', 'An aggregation of interactions and entities into a single process." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000396', 'uncertain process', 'An equivocal or conjectural process, whose existence is assumed but not proven." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000397', 'omitted process', 'One or more processes that are not represented in certain representations or interpretations of a model." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000398', 'logical relationship', 'Relationship between entities (material or conceptual) and logical operators, or between logical operators themselves. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000399', 'decarboxylation', 'A process in which a carboxyl group (COOH) is removed from a molecule as carbon dioxide." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000400', 'decarbonylation', 'Removal of a carbonyl group (-C-O-) from a molecule, usually as carbon monoxide" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000401', 'deamination', 'Removal of an amine group from a molecule, often under the addition of water" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000402', 'transfer of a chemical group', 'Covalent reaction that results in the transfer of a chemical group from one molecule to another." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000403', 'transamination', 'The transfer of an amino group between two molecules. Commonly in biology this is restricted to reactions between an amino acid and an alpha-keto carbonic acid, whereby the reacting amino acid is converted into an alpha-keto acid, and the alpha-keto acid reactant into an amino acid." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000404', 'unit of genetic information', 'Functional entity associated with or derived from a unit of inheritance." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000405', 'perturbing agent', 'A material entity that is responsible for a perturbing effect" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000406', 'observable', 'An entity that can be measured quantitatively" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000407', 'absolute inhibition', 'Control that precludes the execution of a process." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000408', 'biological activity', 'Effect of a biological entity on biological structures or processes." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000409', 'interaction outcome', 'Entity that results from the interaction between other entities." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000410', 'implicit compartment', 'A compartment whose existence is inferred due to the presence of known material entities which must be bounded, allowing the creation of material entity pools." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000411', 'absolute stimulation', 'Control that always triggers the controlled process." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000412', 'biological activity', 'The potential action that a biological entity has on other entities. Example are enzymatic activity, binding activity etc." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000413', 'positional relationship', 'The connectedness between entities as related by their position\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000414', 'cis', 'Positional relationship between entities on the same strand (e.g. in DNA), or on the same side.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000415', 'trans', 'Positional relationship between entities on different sides, or strands" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000416', 'true', 'One of the two values possible from a boolean switch, which equates to 1, on or input." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000417', 'false', 'One of the two values possible from a boolean switch, which equates to 0, off or no input." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000418', 'multimer of complexes', 'Non-covalent association between several independant complexes" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000419', 'multimer of informational molecule segment', 'Non-covalent association between portions of macromolecules that carry genetic information" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000420', 'multimer of macromolecules', 'Non-covalent association between several macromolecules" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000421', 'multimer of simple chemicals', 'Non-covalent association between several simple chemicals" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000422', 'isoinhibition constant', 'Inhibitory constant for the binding of a given ligand with an isomeric form of an enzyme.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000423', 'pseudo-dissociation constant for product', 'In reversible reactions this is the concentration of product that is required to achieve half activation or inhibition in Hill-type kinetics, in the absence of the substrate. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000424', 'pseudo-dissociation constant for substrate', 'In reversible reactions this is the concentration of substrate that is required to achieve half activation or inhibition in Hill-type kinetics, in the absence of the product. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000425', 'reversible Hill-type enzymatic rate law', 'Reversible Hill-type kinetics represents the situation where a single substrate and product bind cooperatively and reversibly to the enzyme. Co-operativity is seen if the Hill coefficient (h) is greater than 1, indicating that the binding of one substrate (or product) molecule facilitates the binding of the next. The opposite effect is evident with a coefficient less than 1. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000426', 'modulated reversible Hill-type rate law', 'Reversible Hill-type kinetics in the presence of at least one modifier whose binding is affected by the presence of the substrate or product." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000427', 'modulated reversible Hill-type rate law with one modifier', 'The modifier can be either an activator or inhibitor depending on the value of alpha (activator for values larger than 1, inhibitor for values smaller than 1; no effect if exactly 1). This reflects the effect of the presence of substrate and product on the binding of the modifier. The equation, derived by Hofmeyr and Cornish-Bowden (Comput. Appl. Biosci. 13, 377 - 385 (1997)" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000428', 'modulated reversible Hill-type rate law with two modifiers', 'The modifiers can be either activators or inhibitors depending on the values of and alpha (activators for values larger than 1, inhibitors for values smaller than 1; no effect if exactly 1). The assumption is that the binding of one modifier affects the binding of the second. Modifiers are assumed to bind at different sites. The synergetic effects of the two modifiers depend on the parameter alpha (if unity then they are independent; if zero they compete for the same binding site). and reflect the effect of the presence of substrate and product on the binding of modifier A or modifier B. alphaA and alphaB factors account for the effect of substrate and product binding on the binding of modifier A and modifier B respectively. alphaAB accounts for the interaction of the modifiers on each others binding.\n (if < 1 Ma is inhibitor, if > 1 activator)\nalpha_2 \t: factor accounting for the effect of S and P on the binding of Mb\n (if < 1 Mb is inhibitor, if > 1 activator)\nalpha_3 \t: factor accounting for interaction of Ma to Mb binding to the enzyme (and v. v.)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000429', 'enzymatic rate law for multireactant enzymes', 'Kinetics of enzyme-catalysed reactions with 2 or more substrates or products\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000430', 'enzymatic rate law for modulated unireactant enzymes', 'Kinetics of enzymes that react with one substance, and whose activity may be positively or negatively modulated." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000431', 'unmodulated reversible Hill-type rate law', 'Reversible equivalent of Hill kinetics, where substrate and product bind co-operatively to the enzyme. A Hill coefficient (h) of greater than 1 indicates positive co-operativity between substrate and product, while h values below 1 indicate negative co-operativity. \n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000432', 'irreversible Michaelis Menten rate law for two substrates', 'Enzymatic rate law for an irreversible reaction involving two substrates and one product." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000433', 'Ordered Bi-Bi mechanism rate law', 'Enzymatic rate law for a reaction involving two substrates and two products. The products P and then Q are released strictly in order, while the substrates are bound strictly in the order A and then B." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000434', 'Ordered Bi-Uni mechanism rate law', 'Enzymatic rate for a reaction involving two substrates and one product. The substrates A and then B are bound strictly in order." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000435', 'Ordered Uni-Bi mechanism rate law', 'Enzymatic rate law for a reaction with one substrate and two products. The products P and then Q are released in the strict order P and then Q." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000436', 'Ping Pong Bi-Bi mechanism rate law', 'Enzymatic rate law for a reaction involving two substrates and two products. The first product (P) is released after the first substrate (A) has been bound. The second product (Q) is released after the second substrate (B) has been bound. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000437', 'reversible Iso Uni-Uni', 'Enzyme catalysed reaction involving one substrate and one product. Unlike the reversible uni-uni mechanism (SBO:0000326), the mechanism assumes an enzyme intermediate. Therefore, the free enzyme generated after the release of product from enzyme-product complex is not the same form as that which bind the substrate to form enzyme-substrate complex. Some permeases are thought to follow this mechanism, such that isomerization in the membrane may be accomplished through re-orientation in the membrane." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000438', 'reversible Uni-Uni', 'The reversible equivalent of the Henri-Michaelis-Menten rate law (SBO:0000029)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000439', 'Uni-Uni Reversible using Haldane relationship', 'Enzyme catalysed reaction involving one substrate and one product. It is a modification of SBO:0000326 that directly incorporates the equilibrium constant in the rate law.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000440', 'enzymatic rate law for irreversible allosteric inhibition', 'Enzymatic rate law which follows from the allosteric concerted model (symmetry model or MWC model).This states that enzyme subunits can assume one of two conformational states (relaxed or tense), and that the state of one subunit is shared or enforced on the others. The binding of a ligand to a site other than that bound by the substrate (active site) can shift the conformation from one state to the other. L represents the equilibrium constant between active and inactive states of the enzyme, and n represents the number of binding sites for the substrate and inhibitor." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000441', 'enzymatic rate law for mixed-type inhibition of reversible enzymes by mutually exclusive inhibitors', 'Reversible inhibition of a unireactant enzyme by inhibitors that can bind to the enzyme-substrate complex and to the free enzyme with the same equilibrium constant. The inhibitor is noncompetitive with the substrate." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000442', 'enzymatic rate law for simple reversible non-competitive inhibition of unireactant enzymes', 'Reversible inhibition of a unireactant enzyme by one inhibitor that can bind to the enzyme-substrate complex and to the free enzyme with the same equilibrium constant. The inhibitor is noncompetitive with the substrate.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000443', 'enzymatic rate law for reversible essential activation', 'Enzymatic rate law where the free enzyme, in the absence of the activator, is unable to bind substrate and has no activity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000444', 'enzymatic rate law for reversible mixed activation', 'Enzymatic rate law where the activator enhances the rate of reaction through specific and catalytic effects, which increase the apparent limiting rate and decrease apparent Michaelis constant. The activator can bind reversibly both the free enzyme and enzyme-substrate complex, while the substrate can bind only to enzyme-activator complex. Catalytic activity is seen only when enzyme, substrate and activator are complexed." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000445', 'enzymatic rate law for irreversible substrate activation', 'This enzymatic rate law is available only for irreversible reactions, with one substrate and one product. There is a second binding site for the enzyme which, when occupied, activates the enzyme. Substrate binding at either site can occur at random.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000446', 'enzymatic rate law for irrreversible mixed activation', 'Enzymatic rate law where the activator enhances the rate of reaction through specific and catalytic effects, which increase the apparent limiting rate and decrease apparent Michaelis constant. The activator can bind irreversibly both free enzyme and enzyme-substrate complex, while the substrate can bind only to enzyme-activator complex. Catalytic activity is seen only when enzyme, substrate and activator are complexed." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000447', 'enzymatic rate law for reversible catalytic activation with one activator', 'Enzymatic rate law where an activator enhances the rate of reaction by increasing the apparent limiting rate; The reversible binding of the activator to the enzyme-substrate complex is required for enzyme catalytic activity (to generate the product). \n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000448', 'enzymatic rate law for reversible specific activation', 'Enzymatic rate law for one substrate, one product and one modifier which acts as an activator. The activator enhances the rate of reaction by decreasing the apparent Michaelis constant. The activator reversibly binds to the enzyme before the enzyme can bind the substrate." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000449', 'enzymatic rate law for irreversible catalytic activation with one activator', 'Enzymatic rate law where an activator enhances the rate of reaction by increasing the apparent limiting rate; The activator binding to the enzyme-substrate complex (irreversibly) is required for enzyme catalytic activity (to generate the product). " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000450', 'enzymatic rate law for irreversible specific activation', 'Enzymatic rate law for one substrate, one product and one modifier which acts as an activator. The activator enhances the rate of reaction by decreasing the apparent Michaelis constant. The activator must bind to the enzyme before the enzyme can bind the substrate. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000451', 'enzymatic rate law for reversible reactions with competitive inhibition', 'This enzymatic rate law involves one substrate, one product and one or more modifiers. The modifiers act as competitive inhibitors of the substrate at the enzyme binding site; The modifiers (inhibitors) reversibly bound to the enzyme block access to the substrate. The inhibitors have the effect of increasing the apparent Km, and bind exclusively to the enzymes." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000452', 'enzymatic rate law for reversible competitive inhibition by one inhibitor', 'This enzymatic rate law involves one substrate, one product and one modifier. The modifier acts as a competitive inhibitor with the substrate at the enzyme binding site; The modifier (inhibitor) reversibly bound to the enzyme blocks access to the substrate. The inhibitor has the effect of increasing the apparent Km. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000453', 'enzymatic rate law for reversible empirical allosteric inhibition by one inhibitor', 'Enzymatic rate law where the reversible binding of one ligand decreases the affinity for substrate at other active sites. The ligand does not bind the same site as the substrate on the enzyme. This is an empirical equation, where n represents the Hill coefficient." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000454', 'enzymatic rate law for reversible substrate inhibition', 'Enzymatic rate law where the substrate for an enzyme also acts as a reversible inhibitor. This may entail a second (non-active) binding site for the enzyme. The inhibition constant is then the dissociation constant for the substrate from this second site." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000455', 'enzymatic rate law for irreversible substrate inhibition', 'Enzymatic rate law where the substrate for an enzyme also acts as an irreversible inhibitor. This may entail a second (non-active) binding site for the enzyme. The inhibition constant is then the dissociation constant for the substrate from this second site.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000456', 'enzymatic rate law for reversible unireactant enzyme with a single hyperbolic modulator', 'Enzymatic rate law where the modifier can act as an activator or inhibitor, depending upon the values of the kinetic constants. The modifier can bind reversibly to all forms of the enzyme and all enzyme-substrate complexes are reactive. \na represents the ratio of dissociation constant of the elementary step Enzyme-Substrate complex + Modifier = Enzyme-Substrate-Modifier complex over that of Enzyme + Modifier = Enzyme-Modifier complex.\nb represents ratio of the rate constant of elementary step Enzyme-Substrate-Modifier complex -> Enzyme-Modifier complex + Product over that of Enzyme-Substrate complex -> Enzyme + Product.\n " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000457', 'enzymatic rate law for irreversible unireactant enzyme with a single hyperbolic modulator', 'Enzymatic rate law where the modifier can act as an activator or inhibitor, depending upon the values of the kinetic constants. The modifier can bind irreversibly to all forms of the enzyme and all enzyme-substrate complexes are reactive. \na represents the ratio of dissociation constant of the elementary step Enzyme-Substrate complex + Modifier = Enzyme-Substrate-Modifier complex) over that of Enzyme + Modifier = Enzyme-Modifier complex.\nb represents ratio of the rate constant of elementary step Enzyme-Substrate-Modifier complex -> Enzyme-Modifier complex + Product over that of Enzyme-Substrate complex -> Enzyme + Product.\n " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000458', 'enzymatic rate law for simple uncompetitive inhibition of reversible unireactant enzymes', 'Reversible inhibition of a unireactant enzyme by one inhibitor, which binds to the enzyme-substrate complex. The inhibitor is uncompetitive with the substrate.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000459', 'stimulator', 'Substance that accelerates the velocity of a chemical reaction without itself being consumed or transformed. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000460', 'enzymatic catalyst', 'A substance that accelerates the velocity of a chemical reaction without itself being consumed or transformed, by lowering the free energy of the transition state. The substance acting as a catalyst is an enzyme." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000461', 'essential activator', 'A substance that is absolutely required for occurrence and stimulation of a reaction." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000462', 'non-essential activator', 'An activator which is not necessary for an enzymatic reaction, but whose presence will further increase enzymatic activity. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000463', 'standard biochemical potential', 'The biochemical potential of a substance measured at standard concentrations and under standard conditions." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000464', 'state variable assignment', 'Assignment of a state or a value to a state variable, characteristic or property, of a biological entity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000465', 'spatial measure', 'The measurable dimensions of an object which are minimally required to define the space that an object occupies." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000466', 'length', 'The length of an object is the longest measurable distance between its extremities. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000467', 'area', 'The area of an object is a quantity expressing its two-dimensional size, usually part or all of its surface. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000468', 'volume', 'A quantity representing the three-dimensional space occupied by all or part of an object." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000469', 'containment', 'An entity that is a subset of another entity or object." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000470', 'mass fraction', 'For a given substance, A, its mass fraction (x A) is defined as the ratio of its mass (m A) to the total mass (m total) in which it is present, where the sum of all mass fractions is equal to 1. This provides a means to express concentration in a dimensionless size. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000471', 'molal concentration of an entity', 'Molality denotes the number of moles of solute per kilogram of solvent (not solution). The term molal solution is used as a shorthand for a \"one molal solution\", i.e. a solution which contains one mole of the solute per kilogram of the solvent. The SI unit for molality is mol/kg." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000472', 'molar concentration of an entity', 'Molarity, or molar concentration, denotes the number of moles of a given substance per litre of solution. The unit of measure of molarity is mol/L, molar, or the capital letter M as an abbreviated form." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000473', 'denotement', 'Term to signify where a material or conceptual entity is represented or denoted by a symbol or by some other abbreviated form. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000474', 'convenience function', 'Mathematical function commonly used in biological modeling, which enable simplification of more complex expressions" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000475', 'periodic forcing function', 'Function that enables the modeling of cyclic inputs with on and off phases, such as the light and dark phases in circadian rhythm. It includes parameters for the on period (Tp), the cycle period (Tc), and the time taken to move or ramp between on and off stages (Tw). Theta0 and Theta1 represent the minimal offset and maximal values of on stage, respectively. Small values of Tw result in step-like changes. Phi is the time of the phase shift offset. In the case of light forcing, Tp represents light period, Tc the cycle period, and Tw the twilight timescale. Theta0 is the light value at the off state, and Theta1 the additional value at the on phase. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000476', 'period', 'The period is the duration of one cycle in a repeating event. \[wikipedia\]" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000477', 'phase shift', 'The measurable amount of time by which a periodic or cyclic is shifted or offset from defined reference point." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000478', 'powered product of Michaelis constant', 'The product of the Michaelis constants, to the power of their respective stoichiometric coefficients, for either substrates or products." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000479', 'powered product of substrate Michaelis constants', 'The product of the substrate Michaelis constants, to the power of their respective stoichiometric coefficients." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000480', 'powered product of product Michaelis constants', 'The product of the product Michaelis constants, to the power of their respective stoichiometric coefficients." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000481', 'stoichiometric coefficient', 'The stoichiometric coefficient represents the degree to which a chemical species participates in a reaction. It corresponds to the number of molecules of a reactant that are consumed or produced with each occurrence of a reaction event." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000482', 'geometric mean rate constant', 'The geometric mean turnover rate of an enzyme in either forward or backward direction for a reaction, measured per second." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000483', 'forward geometric mean rate constant', 'The geometric mean turnover rate of an enzyme in the forward direction for a reaction, measured per second." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000484', 'reverse geometric mean rate constant', 'The geometric mean turnover rate of an enzyme in the reverse direction for a reaction, measured per second." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000485', 'basal rate constant', 'The minimal velocity observed under defined conditions, which may or may not include the presence of an effector. For example in an inhibitory system, this would be the residual velocity observed under full inhibition. In non-essential activation, this would be the velocity in the absence of any activator." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000486', 'relative basal rate constant', 'The ratio of the basal activity to the maximal velocity of a reaction. The values range between 0 and 1." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000487', 'relative activity function', 'Function which ranges from 0 to 1, to describe the relative activation or inhibition of a reaction or process, actual or conceptual. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000488', 'relative activation function', 'Function which ranges from 0 to 1, to describe the relative activation of a reaction or process, actual or conceptual. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000489', 'relative inhibition function', 'Function which ranges from 0 to 1, to describe the relative inhibition of a reaction or process, actual or conceptual. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000490', 'number of products', 'Number of molecules which are generated by an enzyme." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000491', 'diffusion coefficient', 'A proportionality constant representing the amount of substance diffusing across a unit area through a unit concentration gradient in unit time. The higher the diffusion coefficient (of one substance with respect to another), the faster they diffuse into each other. This coefficient has an SI unit of m²/s (length²/time)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000492', 'amplitude', 'Amplitude is the magnitude of change in the oscillating variable, with each oscillation, within an oscillating system. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000493', 'functional domain', 'A spatial region of an entity that confers a function" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000494', 'binding site', 'A specific domain of a spatio-temporal entity to which another spatio-temporal entity is able to bind, forming chemical bonds. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000495', 'catalytic site', 'A catalytic site is the region which confers specificity of a substrate for the binding entity, and where specific reactions take place in the conversion of the substrate to the product. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000496', 'transmembrane domain', 'A transmembrane domain is any three-dimensional protein structure which is thermodynamically stable in a membrane. This may be a single alpha helix, a stable complex of several transmembrane alpha helices, a transmembrane beta barrel, a beta-helix of gramicidin A, or any other structure.\n\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000497', 'ternary switch', 'A parameter that has three discrete values which may be alternated between. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000498', 'relative activity', 'Value which ranges from 0 to 1, to describe the relative activity of a process or reaction. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000499', 'genetic interaction', 'A phenomenon whereby an observed phenotype, qualitative or quantative, is not explainable by the simple additive effects of the individual gene pertubations alone. Genetic interaction between perturbed genes is usually expected to generate a defective phenotype. The level of defectiveness is often used to sub-classify this phenomenon.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000500', 'genetic suppression', 'Genetic suppression is said to have occurred when the phenotypic effect of an initial mutation in a gene is less severe, or entirely negated, by a subsequent mutation. \n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000501', 'genetic enhancement', 'Genetic enhancement is said to have occurred when the phenotypic effect of an initial mutation in a gene is made increasingly severe by a subsequent mutation." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000502', 'synthetic lethality', 'Synthetic lethality is said to have occurred where gene mutations, each of which map to a separate locus, fail to complement in an offspring to correct a phenotype, as would be expected.\n\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000503', 'number of entity pool constituents', 'The numerical quantification of an entity pool. This may be expressed as, for example, the number of molecules or the number of moles of identical entities of which an specific entity pool is comprised." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000504', 'mass of an entity pool', 'The mass that comprises an entity pool." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000505', 'concentration of enzyme', 'Amount of enzyme present per unit of volume. The participant role enzymatic catalyst is defined in SBO:0000460." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000506', 'mass of enzyme', 'Amount, expressed as a mass, of an enzyme. The participant role enzymatic catalyst is defined in SBO:0000460." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000507', 'number of an enzyme', 'Amount, expressed as a number, of a specific enzyme comprising an entity pool. This may be expressed, for example, as the number of molecules, or the number of moles. The participant role enzymatic catalyst is defined in SBO:0000460." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000508', 'number of a reactant', 'The amount, expressed as a number, of a specific reactant comprising an entity pool. This may be expressed, for example, as the number of molecules, or the number of moles. The participant role reactant is defined in SBO:0000010. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000509', 'concentration of reactant', 'The amount of a specific entity pool reactant present per unit of volume. The participant role reactant is defined in SBO:0000010.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000510', 'mass of reactant', 'The amount, expressed as a mass, of a specific reactant entity pool. The participant role reactant is defined in SBO:0000010." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000511', 'number of a product', 'The amount, expressed as a number, of a specific product comprising an entity pool. This may be expressed, for example, as the number of molecules, or the number of moles. The participant role product is defined in SBO:0000011." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000512', 'concentration of product', 'The amount of a specific entity pool product present per unit of volume. The participant role product is defined in SBO:0000011." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000513', 'mass of product', 'The amount, expressed as a mass, of a specific product entity pool. The participant role product is defined in SBO:0000011." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000514', 'number of a substrate', 'The amount, expressed as a number, of a specific substrate comprising an entity pool. This may be expressed, for example, as the number of molecules, or the number of moles. The participant role substrate is defined in SBO:0000015." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000515', 'concentration of substrate', 'The amount of a specific entity pool substrate present per unit of volume. The participant role substrate is defined in SBO:0000015." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000516', 'mass of substrate', 'The amount, expressed as a mass, of a specific substrate entity pool. The participant role substrate is defined in SBO:0000015." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000517', 'number of a modifier', 'The amount, expressed as a number, of a specific modifier comprising an entity pool. This may be expressed, for example, as the number of molecules, or the number of moles. The participant role modifier is defined in SBO:0000019." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000518', 'concentration of modifier', 'The amount of a specific modifier entity pool present per unit of volume. The participant role modifier is defined in SBO:0000019." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000519', 'mass of modifier', 'The amount, expressed as a mass, of a specific modifier entity pool. The participant role modifier is defined in SBO:0000019." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000520', 'number of an inhibitor', 'The amount, expressed as a number, of a specific inhibitor comprising an entity pool. This may be expressed, for example, as the number of molecules, or the number of moles. The participant role inhibitor is defined in SBO:0000020." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000521', 'concentration of inhibitor', 'The amount of a specific inhibitor entity pool present per unit of volume. The participant role inhibitor is defined in SBO:0000020.\n" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000522', 'mass of inhibitor', 'The amount, expressed as a mass, of a specific inhibitor entity pool. The participant role inhibitor is defined in SBO:0000020." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000523', 'number of an activator', 'The amount, expressed as a number, of a specific activator comprising an entity pool. This may be expressed, for example, as the number of molecules, or the number of moles. The participant role activator is defined in SBO:0000459. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000524', 'concentration of activator', 'The amount of a specific activator entity pool present per unit of volume. The participant role activator is defined in SBO:0000459." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000525', 'mass of activator', 'The amount, expressed as a mass, of a specific activator entity pool. The participant role activator is defined in SBO:0000459." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000526', 'protein complex formation', 'The process by which two or more proteins interact non-covalently to form a protein complex (SBO:0000297)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000527', 'modular rate law', 'Modular rate laws are a set of rate laws that provide a means to parameterise a system in a manner that is a compromise between mathematical abstraction and biochemical detail. They share the same common form:\n\nv = u f (T/(D + Dreg))\n\nThe individual numerator and denominator terms can substituted with alternative forms, depending on reaction details and model formulation, to generate specific modular rate laws. The terms represented are;\nv, reaction rate;\nu, enzyme amount;\nT, modular term derived from stoichiometries, metabolite concentrations and reactant constants;\nD, modular term for polynomial of scaled concentrations;\nDreg, competitive regulation binding states term;\nf, modular term for regulation factor." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000528', 'common modular rate law', 'The common modular rate law is a generalised form of reversible Michaelis Menten kinetics, using a denominator where each binding state of the enzyme is represented. It is assumed that substrates and products bind independently and randomly, and that substrates and products cannot be bound at the same time." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000529', 'direct binding modular rate law', 'The direct binding modular rate law makes the assumption that both substrates and products bind simultaneously and in a single step, hence the total binding states possible enumerate to 3; nothing bound, substrates bound, and products bound. Substrates and products cannot be bound at the same time." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000530', 'simultaneous binding modular rate law', 'The simultaneous binding modular rate law makes the assumption that substrates and products can be bound simultaneously, and in any combination." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000531', 'power-law modular rate law', 'For the power-law rate law, the denominator is set to be a constant, and the rate law does not saturate." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000532', 'force-dependent modular rate law', 'Modular rate law where the D term is given by the square root of the product of\nterms (c/KM)^m where c, KM, and m denote the concentrations, Michaelis constants, and molecularities, respectively, and the product is taken over all reactants and products involved in the reaction." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000533', 'specific activator', 'An essential activator that affects the apparent value of the specificity\nconstant. Mechanistically, the activator would need to be bound before\nreactant and product binding can take place." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000534', 'catalytic activator', 'An essential activator that affects the apparent value of the catalytic\nconstant." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000535', 'binding activator', 'An essential activator that affects the apparent value of the Michaelis\nconstant(s)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000536', 'partial inhibitor', 'Substance that, when bound, decreases enzymatic activity to a lower,\nnonzero value, without itself being consumed or transformed by the\nreaction, and without sterically hindering the interaction between\nreactants. The enzyme-inhibitor complex does retain some basal level of activity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000537', 'complete inhibitor', 'Substance that, when bound, completely negates enzymatic activity, without\nitself being consumed or transformed by the reaction, and without\nsterically hindering the interaction between reactants. The inhibitor\nbinds to all enzyme species independently and with the same affinity,\ncompletely inhibiting any enzymatic activity." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000538', 'ionic permeability', 'A parameter that represents the permeability of an ion channel with respect to a particular ion." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000539', 'probabilistic parameter', 'A quantitative parameter that represents a probability value, assigned to a specific event." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000540', 'fraction of an entity pool', 'A ratio that represents the quantity of a defined constituent entity over the total number of all constituent entities present. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000541', 'mole fraction', 'The number of moles of a constituent entity, divided by the total number of all constituent entities present in a system. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000542', 'basic reproductive ratio', 'An epidemiological term representing the mean number of secondary cases which result from a single infection, where the population under consideration has no immunity, and no intervention is performed." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000543', 'protein aggregate', 'A nonspecific coalescence of misfolded proteins which may or may not form a precipitate, depending upon particle size." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000544', 'metadata representation', 'Supplementary information relating to a primary item of data, traditionally termed data about data. It can describe, for example, the location or type of the data, or its relationship to other data." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000545', 'systems description parameter', 'A value, numerical or symbolic, that defines certain characteristics of systems or system functions, or is necessary in their derivation." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000546', 'qualitative systems description parameter', 'A non-numerical value that defines certain characteristics of systems or system functions." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000547', 'boolean logical framework', 'Equationally defined algebraic framework usually interpreted as a two-valued logic using the basic Boolean operations (conjunction, disjunction and negation), together with the constants 0 and 1 denoting false and true values, respectively." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000548', 'multi-valued logical framework', 'Extension of the boolean logical framework which associates a defined number of possible integer values (states) with the variables." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000549', 'fuzzy logical framework', 'Extension of the Boolean logical framework which allows intermediate or undetermined values for the logical variables." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000550', 'annotation', 'Supplementary information that does not modify the semantics of the presented information." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000551', 'controlled short label', 'The use of an abbreviated name, taken from a controlled vocabulary of terms, which is used to represent some information about the entity to which it is attached." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000552', 'reference annotation', 'Additional information that supplements existing data, usually in a document, by providing a link to more detailed information, which is held externally, or elsewhere." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000553', 'bibliographical reference', 'An annotation which directs one to information contained within a published body of knowledge, usually a book or scientific journal." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000554', 'database cross reference', 'An annotation which directs one to information contained within a database." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000555', 'controlled annotation', 'Annotation which complies with the full set of defined rules in its construction." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000556', 'uncontrolled annotation', 'Annotation which does not comply with, or is not restricted by, any rules in its construction. Examples would include free text annotations." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000557', 'embedded annotation', 'Annotation that directly incorporates information into the body of a document." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000558', 'specific activity', 'A measure of enzyme activity under standard conditions, at a specific substrate concentration (usually saturation), expressed as the amount of product formed per unit time, per amount of enzyme. This is often expressed as micromol per min per mg, rather than the less practical official unit, Katal (1 mol per second)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000559', 'enzyme activity', 'A measure of the amount of active enzyme present, expressed under specified conditions. This is often expressed as micromol per min (also known as enzyme unit, U), rather than the less practical official SI unit, Katal (1 mol per second). Enzyme activity normally refers to the natural substrate for the enzyme, but can also be given for standardised substrates such as gelatin, where it is then referred to as GDU (Gelatin Digesting Units)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000560', 'mass action rate law for first order irreversible reactions, single essential stimulator, continuous scheme', 'Reaction scheme in which the reaction velocity is direct proportional to the activity or concentration of a single molecular species. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of the stimulator. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000561', 'mass action rate law for first order irreversible reactions, single essential stimulator, discrete scheme', 'Reaction scheme in which the reaction velocity is direct proportional to the activity or quantity of a single molecular species. The reaction scheme does not include any reverse process that creates the reactants from the products. The change of a product quantity is proportional to the quantity of the stimulator. It is to be used in a reaction modelled using a discrete framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000562', 'mass action like rate law for second order irreversible reactions, one reactant, one essential stimulator', 'Reaction scheme where the products are created from a reactant and the change of a product quantity is proportional to the product of the reactant and the stimulator activities. The reaction scheme does not include any reverse process that creates the reactant from the products. The change of a product quantity is proportional to the quantity of the reactant and the stimulator. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000563', 'mass action like rate law for second order irreversible reactions, one reactant, one essential stimulator, continuous scheme', 'Reaction scheme where the products are created from a reactant and the change of a product quantity is proportional to the product of the reactant and the stimulator activities. The reaction scheme does not include any reverse process that creates the reactant from the products. The change of a product quantity is proportional to the quantity of the reactant and the stimulator. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000564', 'mass action like rate law for second order irreversible reactions, one reactant, one essential stimulator, discrete scheme', 'Reaction scheme where the products are created from a reactant and the change of a product quantity is proportional to the product of the reactant and the stimulator quantities. The reaction scheme does not include any reverse process that creates the reactant from the products. The change of a product quantity is proportional to the quantity of the reactant and the stimulator. It is to be used in a reaction modelled using a discrete framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000565', 'systems description constant', 'A physical constant that is required in the calculation of a system parameter. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000566', 'relative permeability', 'The permeability of an ion through a channel or membrane expressed in relation to the reference ion, which is given the value 1. For example, if a membrane is most permeable to K+, then that is assigned the reference permeability value of 1, and the value for Na+ may be 0.05." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000567', 'universal gas constant', 'A physical constant featured in many fundamental equations in the physical sciences. It is equivalent to the Boltzmann constant, but expressed in units of energy per temperature increment per mole (rather than energy per temperature increment per particle). It has the value 8.314 J.K-1.mol-1 and is denoted by the symbol R." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000568', 'Faraday constant', 'Named after Michael Faraday, it is the magnitude of electric charge per mole of electrons. It has the value 96,485.3365 C/mol (Coulombs per Mole), and the symbol F." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000569', 'Goldman equation', 'Expression to determine the equilibrium potential (membrane potential) across a cellular membrane, taking into consideration all the ions on either side of the membrane, and their permeability through the membrane. Permeability values are often recorded as relative permeability, with the most permeable ion being given a reference value of 1. The unit of measure for membrane potential is Volts, though values are typically reported as millivolts (mV).\nThe given formula represents the voltage equation for C monovalent cations, and A monovalent anions, assuming that C is the most permeable, and thereby reporting all other permeabilities as a proportion of the reference value, of 1. P represents the membrane permeability of C (assumed reference molecule, value 1); p, the relative permeability of each non-reference molecule; C, the external monovalent cation; c, the internal monovalent cation concentration; A, the external monovalent anion; a, the internal monovalent anion concentration; R, the universal gas constant; T, the temperature in Kelvin; F the Faraday constant." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000570', 'Nernst potential', 'The membrane potential at which there is no net flow of an ions across a biological membrane. In a single ion system, this is equal to the equilibrium potential and can be calculated from the Nernst equation. It takes into consideration the charge, z, of the ion, as well as its concentration inside (x) and outside (X) the membrane." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000571', 'thermodynamic parameter', 'Parameters used in the study of thermodynamics, a physical science that\npertains to the relationship between heat and other forms of energy such\nas work done in material bodies." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000572', 'enthalpy', 'A thermodynamic potential whose natural variables are entropy (S) and\npressure (p). The enthalpy of a system, measured in Joules (J), is defined\nas H = U + pV (where H is enthalpy, U is the internal energy, p is the\npressure at the system boundary, and V is the system volume).\nsymbol: H" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000573', 'enthalpy change', 'Change in enthalpy observed in the constituents of a thermodynamic system\nwhen undergoing a transformation or chemical reaction. This is the\npreferred way of expressing the energy changes to a system at constant\npressure, since enthalpy itself cannot be directly measured. The enthalpy\nchange is positive in endothermic reactions, negative in exothermic\nreactions, and is defined as the difference between the final and initial enthalpy of the system under study: ΔH = Hf - Hi. The standard unit of measure is J. Symbol: ΔH" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000574', 'standard enthalpy of formation', 'The enthalpy change observed in a constituent of a thermodynamic system\nwhen one mole of a compound, in its standard state, is formed from its\nelementary antecedents, in their standard state(s), under standard\nconditions (1 bar). The standard unit of measure is kJ/mol.\nSymbol: DeltaHf0, DeltafH0" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000575', 'standard enthalpy of reaction', 'The enthalpy change observed in a constituent of a thermodynamic system\nwhen one mole of substance reacts completely, under standard conditions (1\nbar). The standard unit of measure is kJ/mol.\nSymbol: DeltaHr0, DeltarH0" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000576', 'entropy', 'A thermodynamic property which acts as a measure of the state of disorder\nof a system. Its natural variables are the internal energy (U) and the\nvolume (V). It is defined by dS = (1/T)dU + (p/T)dV. The second law of\nthermodynamics states that in an isolated system, natural processes tend\nto increase in disorder or entropy. The standard unit of measure is Joules\nper Kelvin (J/K).\nsymbol: S" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000577', 'entropy change', 'The increase or decrease of the entropy of a system. For values greater\nthan zero, there is an implied increase in the disorder of a system, for\nexample during a reaction, and decreased disorder where the values are\nless than zero. The entropy change of a process is defined as the initial\nsystem entropy value minus the final entropy value: DeltaS = Sf - Si. The\nstandard unit of measure is J/K.\nsymbol: DeltaS" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000578', 'standard entropy of reaction', 'The entropy change observed in a thermodynamic system when one mole of\nsubstance reacts completely, under standard conditions (1 bar). The\nstandard unit of measure is kJ/(mol K). This can be calculated using the\nentropies for products and reactants: DeltaS(reaction)=sum DeltaS (products) - sum DeltaS reactants. The standard unit of measure is kJ/(mol K).\nsymbol: DeltaSro" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000579', 'standard entropy of formation', 'The change in entropy associated with the formation of one mole of a\nsubstance from its elements in their standard states under standard\nconditions (1 bar). The standard unit of measure is kJ/(mol K).\nsymbol: DeltaSfo" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000580', 'Gibbs free energy', 'A thermodynamic potential that measures the useful work obtainable from a\nthermodynamic system at constant pressure and temperature. Its natural\nvariables are pressure (p) and temperature (T) and the definition is: G =\nH - TS. Gibbs free energy is minimised when a system reaches equilibrium\nat constant pressure and temperature. The standard unit of measure is\nkJ/mol.\nsymbol: G" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000581', 'Gibbs free energy change', 'The increase or decrease of the Gibbs free energy of a system. During a\nreaction, this is equal to the change in enthalpy of the system minus the\nchange in the product of the temperature times the entropy of the system: ΔG = ΔH - T ΔS. A negative value indicates that the reaction will be favoured and will\nrelease energy. The magnitude of the value indicates how far the reaction\nis from equilibrium, where there will be no free energy change. The\nstandard unit of measure is kJ/mol. Symbol: ΔG." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000582', 'standard Gibbs free energy of formation', 'The change in Gibbs free energy associated with the formation of 1 mole of substance from elements in their standard states under standard conditions (1 bar). For aqueous solutions, each solute must be present in 1M concentration. The standard unit of measure is kJ/mol. Symbol: ΔGf°." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000583', 'standard Gibbs free energy of reaction', 'The Gibbs free energy change observed in a thermodynamic system when one\nmole of substance reacts completely, under standard conditions (1 bar). For aqueous solutions, each solute must be present in 1M concentration. The standard unit of measure is kJ/mol. Symbol: ΔG°." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000584', 'temporal offset', 'A duration of time after which a phase shift occurs." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000585', 'simulation duration', 'The total length of time over which a model is simulated, where the time scale is indicated within the model simulation. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000586', 'model time', 'A conceptualisation of time which is intrinsic to a mathematical model, and which can be used to describe other variables or parameters of the model." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000587', 'transcellular membrane influx reaction', 'A transport reaction which results in the entry of the transported entity, into the cell." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000588', 'transcellular membrane efflux reaction', 'A transport reaction which results in the removal of the transported entity from the cell." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000589', 'genetic production', 'A composite biochemical process through which a gene sequence is fully converted into mature gene products. These gene products may include RNA species as well as proteins, and the process encompasses all intermediate steps required to generate the active form of the gene product." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000590', 'promoter', 'A stretch of DNA upstream of a transcription start site, to which a promoter and other transcription factors may bind to initiate or regulate expression." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000591', 'petri net transition', 'A process that can modify the state of petri net places\[SBO:0000593\]." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000592', 'discrete amount of an entity pool', 'A discrete value attributed to an entity pool." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000593', 'petri net place', 'A defined entity pool state which can be modified by a petri net transition \[SBO:0000591\]. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000594', 'neutral participant', 'A participant whose presence does not alter the velocity of a process or event. " [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000595', 'dual-activity modifier', 'A modifier that can exhibit either inhibitory or stimulatory effects on a\nprocess depending on the context in which it occurs. For example, the observed effect may be dependent upon the concentration of the modifier." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000596', 'modifier of unknown activity', 'A modifier whose activity is not known or has not been specified." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000597', 'silencer', 'A silencer is a modifier which acts in a manner that completely prevents an event or process from occurring. For example, a silencer in gene expression is usually a transcription factor that binds a DNA sequence in such a way as to completely prevent the binding of RNA polymerase, and thus fully suppresses transcription." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000598', 'promoter', 'A region of DNA to which various transcription factors and RNA polymerase must bind in order to initiate transcription for a gene." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000599', 'port', 'A denotement that specifies a point of contact between variables or submodels in a hierarchical model." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000600', 'input port', 'A connection point to an element in a model that indicates that the elements mathematical interpretation is defined outside the model." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000601', 'output port', 'A connection point to an element in a model that indicates that the elements mathematical interpretation is defined within the model." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000602', 'logical parameter', 'A parameter that takes only logical values." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000603', 'side product', 'A substance that is produced in a chemical reaction but is not itself the primary product or focus of that reaction. Examples include, but are not limited to, currency compounds such as ATP, NADPH and protons." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000604', 'side substrate', 'A substance that is consumed in a chemical reaction but is not itself the primary substrate or focus of that reaction. Examples include, but are not limited to, currency compounds such as ATP, NADPH and protons." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000605', 'high affinity receptor', 'A receptor where binding occurs through strong intermolecular forces such as Van der Waals, hydrogen bonds or ionic bonds." [SBO:team "https://en.wikipedia.org/wiki/Ligand_%28biochemistry%29"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000606', 'low affinity receptor', 'A receptor where binding occurs through weak intermolecular forces." [SBO:team "https://en.wikipedia.org/wiki/Ligand_%28biochemistry%29"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000607', 'dimer', 'A macromolecular complex composed of two monomeric units, which may or may not be identical. Monomers are usually non-covalently bound." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000608', 'homodimer', 'A macromolecular complex composed of precisely two identical monomeric units, which are usually non-covalently bound." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000609', 'heterodimer', 'A macromolecular complex composed of precisely two non-identical monomeric units, which are usually non-covalently bound." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000610', 'growth rate', 'A measure of the rate of growth of an organism, usually in culture. This can be expressed as increase in cell number or, more usually as an increase in dry weight of cells (grams), measured over a unit time period. Usually expressed as hour -1." [SBO:team "http://goldbook.iupac.org/G02709.html"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000611', 'effective catalytic rate', 'Under nutrient limited conditions, it may be assumed that enzymes are operating below their maximal capacity (Kcat). Keff represents the lumped turnover rate of a reaction, expressed in units per time." [SBO:team "see supplementary material for http://identifiers.org/pubmed/24084808"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000612', 'rate of reaction', 'The velocity at which a reaction occurs. This may be calculated through the accumulation of a product or consumption of a reactant, and expressed using entity concentrations or amounts per time interval. The rate of reaction may be influenced by temperature, pressure and other factors. Rate of reaction is often referred to as reaction rate or metabolic flux." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000613', 'reaction parameter', 'Parameters that pertain to chemical reactions." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000614', 'rate of reaction (concentration)', 'Rate of reaction expressed as a change in concentration over time." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000615', 'rate of reaction (amount)', 'Rate of reaction expressed as a change in enumerated quantity over time." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000616', 'extent of reaction', 'The extent of a reaction is a measure of how far a reaction has proceeded towards equilibrium. It is denoted by the Greek letter ξ and is expressed in moles." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000617', 'Gibbs free energy of reaction', 'The Gibbs free energy change observed in a thermodynamic system when a substance undergoes a reaction under non standard conditions. The unit of measure is kJ/mol. Symbol: ΔG." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000618', 'reaction affinity', 'The negative partial derivative of Gibbs free energy G with respect to extent of reaction at constant pressure and temperature. Affinity is positive for spontaneous reactions in the forward direction. Symbol: ξ." [SBO:team "https://en.wikipedia.org/wiki/Chemical_affinity"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000619', 'transformed Gibbs free energy change', 'A Gibbs free energy that is calculated from the standard Gibbs value (at 298K), and extrapolated to a desired pH and ionic strength, and may be determined at a different temperature. Symbol: ΔG´." [SBO:team "http://www.ncbi.nlm.nih.gov/pubmed/9578607"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000620', 'transformed standard Gibbs free energy of reaction', 'A Gibbs free energy of reaction that is calculated from the standard Gibbs value (at 298K), and extrapolated to a desired pH and ionic strength, and may be determined at a different temperature. Symbol ΔG´." [SBO:team "http://www.ncbi.nlm.nih.gov/pubmed/9578607"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000621', 'transformed standard Gibbs free energy of formation', 'A Gibbs free energy of formation that is calculated from the standard Gibbs value (at 298K), and extrapolated to a desired pH and ionic strength, and may be determined at a different temperature. Symbol ΔGf´." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000622', 'transformed Gibbs free energy of reaction', 'The Gibbs free energy change observed in a thermodynamic system when a substance undergoes a reaction under non standard conditions, which is extrapolated to a desired pH and ionic strength, and may be determined at a different temperature. Symbol: ΔG´." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000623', 'ionic strength', 'A combined (weighted) measure of the concentration of all electrolytes present in a solution. It is calculated as a half of the sum over all the ions in the solution multiplied by the square of individual ionic valencies. Monovalent electrolytes have a concentration equal to their ionic strength while multivalent electrolytes have greater ionic strength, directly proportional to ionic valency. Symbol: I" [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000624', 'flux balance framework', 'Modelling approach, typically used for metabolic models, where the flow of metabolites (flux) through a network can be calculated. This approach will generally produce a set of solutions (solution space), which may be reduced using objective functions and constraints on individual fluxes." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000625', 'flux bound', 'A parameter that limits the upper or lower value that a flux may assume. This parameter may be determined experimentally, or may be the result of theoretical investigation." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000626', 'default flux bound', 'A value used for flux bound in cases where a precise value, supported experimentally or theoretically, is not available." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000627', 'exchange reaction', 'A modeling process to provide matter influx or efflux to a model, for example to replenish a metabolic network with raw materials (eg carbon / energy sources). Such reactions are conceptual, created solely for modeling purposes, and do not have a physical correspondence. Exchange reactions, often represented as R_EX_, can operate in the negative (uptake) direction or positive (secretion) direction. By convention, a negative flux through an exchange reaction represents uptake of the corresponding metabolite, and a positive flux represent discharge." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000628', 'demand reaction', 'A modeling process analogous to exchange reaction, but which operates upon \"internal\" metabolites. Metabolites that are consumed by these reactions are assumed to be used in intra-cellular processes that are not part of the model. Demand reactions, often represented R_DM_, can also deliver metabolites (from intra-cellular processes that are not considered in the model)." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000629', 'biomass production', 'Biomass production, often represented R_BIOMASS_, is usually the optimization target reaction of constraint-based models, and can consume multiple reactants to produce multiple products. It is also assumed that parts of the reactants are also consumed in unrepresented processes and hence products do not have to reflect all the atom composition of the reactants. Formulation of a biomass production process entails definition of the macromolecular content (eg. cellular protein fraction), metabolic constitution of each fraction (eg. amino acids), and subsequently the atomic composition (eg. nitrogen atoms). More complex biomass functions can additionally incorporate details of essential vitamins and cofactors required for growth." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000630', 'ATP maintenance', 'A modeling representation of the energetics of an organism that are attributed to energy costs not directly related to those for growth." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000631', 'pseudoreaction', 'A conceptual process used for modeling purposes, often created solely to complete model structure, with respect to providing inflow or outflow of matter or material. Unlike other reactions, pseudoreactions are not usually subjected to mass balance considerations." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000632', 'sink reaction', 'A modeling process to provide matter influx or efflux to a model, for example to replenish a metabolic network with raw materials (eg carbon / energy sources). Such reactions are conceptual, created solely for modeling purposes, and do not have a physical correspondence. Unlike the analogous demand (SBO:....) reactions, which are usually designated as irreversible, sink reactions always represent a reversible uptake/secretion processes, and act as a metabolite source with no cost to the cell. Sink reactions, also referred to as R_SINK_, are generally used for compounds that are metabolized by the cell but are produced by non-metabolic, un-modeled cellular processes." [SBO:team "identifiers.org/pubmed/20057383"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000633', 'subsystem', 'Term used to indicate the grouping of model components, largely reactions, by some criterion, often processual. This can be used to indicate, for example, the subsystem of a model that is concerned with transport. A designated subsystem includes reactions annotated with the term, as well as reactions participants such as enzymes, modifiers and genes encoding these subsystem components." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000634', 'DNA segment', 'Fragment or region of a DNA macromolecule." [SBO:team "http://identifiers.org/so/SO:0000997"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000635', 'RNA segment', 'Fragment or region of an RNA macromolecule." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000636', 'allosteric activator', 'Describes an activator (ligand) which binds at a site other than the active site, resulting in a conformational change, enhancing the activity of the enzyme." [SBO:team "https://en.wikipedia.org/wiki/Allosteric_regulation", SBO:team "http://www.biopax.org/release/biopax-level3-documentation.pdf"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000637', 'non-allosteric activator', 'Describes an activator (ligand) which binds to the enzyme, which does not result in a conformational change, but which enhances the enzymes activity." [SBO:team "http://www.biopax.org/release/biopax-level3-documentation.pdf"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000638', 'irreversible inhibitor', 'An inhibitor which binds irreversibly with the enzyme such that it cannot be removed, and abolishes enzymatic function." [SBO:team "http://www.biopax.org/release/biopax-level3-documentation.pdf"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000639', 'allosteric inhibitor', 'An inhibitor whose binding to an enzyme results in a conformational change, resulting in a loss of enzymatic activity. This activity can be restored upon removal of the inhibitor." [SBO:team "http://www.biopax.org/release/biopax-level3-documentation.pdf"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000640', 'uncompetitive inhibitor', 'An inhibitor which binds only to the complex formed between the enzyme and substrate (E-S complex)." [SBO:team "https://en.wikipedia.org/wiki/Uncompetitive_inhibitor", SBO:team "http://www.biopax.org/release/biopax-level3-documentation.pdf"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000641', 'pMg', 'An enumeration of the concentration of magnesium (Mg) in solution (pMg = -log10\[Mg2+\])." [SBO:team "http://identifiers.org/pubmed/1567986');
INSERT INTO soterms (id, name, definition) VALUES ('0000642', 'inhibited', 'Conceptual or material entity that is the object of an inhibition process, and is acted upon by an inhibitor." [SBO:team "http://identifiers.org/biomodels.sbo/SBO:0000020"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000643', 'stimulated', 'Conceptual or material entity that is the object of a stimulation process, and is acted upon by a stimulator." [SBO:team "http://identifiers.org/biomodels.sbo/SBO:0000459"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000644', 'modified', 'Conceptual or material entity that is the object of a modification process, and is acted upon by a modifier." [SBO:team "http://identifiers.org/biomodels.sbo/SBO:0000019"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000645', 'template', 'An entity that acts as the starting material for genetic production (http://identifiers.org/biomodels.sbo/SBO:0000589)." [SBO:team "http://identifiers.org/biomodels.sbo/SBO:0000589"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000646', 'mass action rate law for reversible reactions, continuous schema', 'Reaction scheme where the products are created from the reactants and the change of a product quantity is proportional to the product of reactant activities. The reaction scheme includes a reverse process that creates the reactants from the products. It is to be used in a reaction modelled using a continuous framework." [src_code:NR]');
INSERT INTO soterms (id, name, definition) VALUES ('0000647', 'molecular mass', 'A measure of the mass of a molecule derived as a sum of weights of its constituent elements multiplied by the number of atoms of each of the element described by its molecular formula. It is commonly represented using units of daltons." [SBO:team "https://en.wikipedia.org/wiki/Molecular_mass"]');
INSERT INTO soterms (id, name, definition) VALUES ('0000648', 'protein molecular mass', 'A measure of the total mass of a protein described as a sum total of the weight of all its atoms. It is commonly represented using units of daltons." [src_code:NR]');